therapeutic action: anti-inflammatory

Andorran ethnomycology: culinary uses and beyond

This research documents how people in Andorra traditionally use wild mushrooms for food and medicine. Researchers interviewed 131 older residents and found 50 different types of mushrooms being used, with over 150 local names for them. Most uses were for cooking (97%), with mushrooms being dried, pickled, or frozen. The study identified several mushrooms that might be valuable for future nutritional research and product development.

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The complete mitochondrial genome of medicinal fungus Taiwanofungus camphoratus reveals gene rearrangements and intron dynamics of Polyporales

Scientists have decoded the complete genetic blueprint of the mitochondria in Taiwanofungus camphoratus, a highly valued medicinal mushroom from Taiwan. This fungus has been used in traditional medicine for treating inflammation, cancer, and liver diseases. By comparing its mitochondrial DNA with related fungal species, researchers discovered that this mushroom has a unique genetic arrangement and uncovered how genes have been rearranged during evolution. This discovery helps scientists better understand how this important medicinal fungus evolved and can improve its classification and medical applications.

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Comparative transcriptome analysis reveals the genetic basis underlying the biosynthesis of polysaccharides in Hericium erinaceus

Researchers studied six different strains of lion’s mane mushrooms to understand how they produce beneficial compounds called polysaccharides. Using advanced genetic analysis, they identified thirteen key genes responsible for making these health-promoting molecules. The study found that a strain called PZH-05 produced the most polysaccharides, and its genes were more active than in other strains. This research helps explain why lion’s mane mushrooms are effective for boosting immunity, fighting cancer, and managing blood sugar.

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Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages

This study analyzed the chemical composition of Scorias spongiosa, an edible fungus, at different stages of growth using advanced laboratory techniques. Researchers found that the fungus contains beneficial compounds with antioxidant, anti-inflammatory, and other health-promoting properties. The study recommends harvesting the fungus at its earliest growth stage to preserve the most beneficial compounds for food and nutritional products.

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Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

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Enhanced Heat Resistance in Morchella eximia by Atmospheric and Room Temperature Plasma

Researchers used a special plasma technology to create heat-resistant strains of morel mushrooms that can thrive at higher temperatures. These mutant strains showed enhanced natural defense systems with more antioxidant enzymes and protective compounds. This breakthrough could help farmers grow more morels successfully despite rising temperatures from climate change, while maintaining their nutritional and medicinal benefits.

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Enhancement and Mechanism of Ergosterol Biosynthesis in Termite Ball Fungus Athelia termitophila by Methyl Jasmonate

Scientists studied how to increase ergosterol production in termite ball fungus, a medicinal fungus used in traditional medicine. By adding methyl jasmonate, a natural signaling molecule, they more than doubled ergosterol content. Ergosterol is used to make vitamin D2 and certain medications for inflammation and cancer. The study identified which genes need to be activated for better ergosterol production, providing insights for creating more effective medical products from fungi.

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Identification of potential neuroprotective compound from Ganoderma lucidum extract targeting microtubule affinity regulation kinase 4 involved in Alzheimer’s disease through molecular dynamics simulation and MMGBSA

Researchers used computer simulations to test five compounds from Reishi mushrooms against Alzheimer’s disease. They found that two compounds, ganoderic acid A and ganoderenic acid B, showed strong potential for blocking a harmful protein involved in the disease. These findings suggest Reishi mushrooms could be a source for new Alzheimer’s treatments, though further laboratory testing is needed.

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Whole genome sequencing and annotations of Trametes sanguinea ZHSJ

Scientists sequenced the complete genome of Trametes sanguinea, a medicinal mushroom used in traditional Chinese medicine, grown in China. The mushroom’s tissue contains beneficial compounds that may help fight tumors, protect the heart, boost immunity, and heal diabetic wounds. By mapping out all 10,886 genes in this fungus, researchers now have detailed blueprints to understand how it produces these healing compounds and potentially grow them industrially for medical use.

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Endophytic Fungi Isolated from the Brown Alga Sargassum thunbergii in Coastal Korea

Researchers isolated six previously unknown fungal species living inside the brown seaweed Sargassum thunbergii collected from Korean coastal waters. These fungi, identified through genetic analysis and physical characteristics, belong to families known for producing compounds with antimicrobial and anti-inflammatory properties. The discovery reveals that seaweeds harbor a diverse community of fungi that could potentially be used to develop new medicines and agricultural products.

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