therapeutic action: anti-inflammatory

Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites

Scientists studied a medicinal mushroom species to understand how different growing methods affect its beneficial compounds. They found that growing the mushroom on specific wood substrates (from cinnamon trees) produced much higher levels of therapeutic compounds compared to rice-based cultivation. Using advanced molecular techniques, they identified the genes responsible for producing these medicinal compounds and how they are controlled, providing insights to improve mushroom cultivation for better health benefits.

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Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

Cordyceps militaris is a medicinal fungus used traditionally for treating fatigue, boosting immunity, and managing various health conditions. This comprehensive review explains how different growing methods, nutrients, light, temperature, and substrate materials affect the production of beneficial compounds in the fungus. The findings show that mixing grains with insect materials and using specific light conditions can significantly increase production of cordycepin, the most promising compound for cancer and immune health. The review identifies that more standardized growing methods and better understanding of the fungus’s metabolism are needed to make large-scale production practical and affordable.

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Insights into microbiome-triterpenoid correlation in Poria cocos via comparative analysis of sclerotial and soil microenvironments

This study explores how the medicinal mushroom Poria cocos creates its own special microbial environment inside its sclerotium (the part used in medicine). Researchers found that the mushroom selectively enriches certain bacteria and fungi while maintaining lower overall microbial diversity compared to surrounding soil. The study reveals that specific microbes like Burkholderia and Scytalidium are positively associated with the production of pachymic acid, the mushroom’s key medicinal compound with anti-tumor and anti-inflammatory properties.

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Evaluation of Salvia yangii Extract as a Promising Protective Raw Material Applied Topically to the Skin

Russian Sage (Salvia yangii) extract shows promise as a natural ingredient for skincare products. The study found that the plant contains compounds like rosmarinic acid that provide antioxidant, antimicrobial, and anti-aging benefits. When used at appropriate concentrations, the extract protected skin cells from sun damage and helped inhibit enzymes that break down skin collagen. This research supports the use of S. yangii in developing safer, more effective natural cosmetic products.

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High Efficiency In Vitro Wound Healing of Dictyophora indusiata Extracts via Anti-Inflammatory and Collagen Stimulating (MMP-2 Inhibition) Mechanisms

This study examines bamboo mushroom extracts for their ability to promote skin wound healing. Researchers tested three different parts of immature bamboo mushrooms and found that the core extract was particularly effective at reducing inflammation and preventing excessive collagen breakdown, which helps wounds heal properly without excessive scarring. The extract performed as well as or better than standard pharmaceutical agents, suggesting it could be a promising natural ingredient for wound healing products.

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Pan-genomic characterization and structural variant analysis reveal insights into spore development and species diversity in Ganoderma

Researchers completed the first comprehensive genome study of 15 Ganoderma (Lingzhi/Reishi) varieties, including five new Chinese strains. They discovered that specific genetic changes in the MSH4 gene dramatically increase spore production in one superior strain. These findings help explain why different Ganoderma varieties have different medicinal properties and can guide breeding of better medicinal mushroom varieties.

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Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand

This study examined how oyster mushrooms change nutritionally and chemically as they mature from young to fully grown. Researchers found that while mature mushrooms have more overall nutrients and starch-like compounds, younger middle-stage mushrooms have higher levels of beneficial antioxidant compounds and special substances that may help manage blood sugar. The findings suggest that when and how you harvest mushrooms matters for what health benefits they provide, helping farmers and food makers decide when to pick mushrooms based on what they want to produce.

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Natural Neuroinflammatory Modulators: Therapeutic Potential of Fungi-Derived Compounds in Selected Neurodegenerative Diseases

This comprehensive review explores how compounds found in mushrooms could help treat serious brain diseases like Alzheimer’s and Parkinson’s disease. Mushrooms contain natural substances such as certain carbohydrates, proteins, and fats that can reduce harmful inflammation in the brain and protect nerve cells from damage. Scientists have tested these mushroom-derived compounds in laboratory and animal models, finding they can improve memory, movement, and overall brain function. This research suggests mushrooms could become an important part of new treatments for these currently incurable neurological conditions.

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FTIR Characterization and Bioactivity Assessment of Cinnamomum camphora Essential Oil: Antioxidant, Anti-Enzymatic, and Antifungal Properties Against Phytopathogens

Camphor tree essential oil shows promise as a natural, eco-friendly fungicide for protecting crops from fungal diseases. The oil demonstrated strong antifungal activity against several common plant pathogens while also possessing antioxidant and potential antidiabetic properties. This makes it a valuable candidate to replace harmful synthetic pesticides in agriculture, offering benefits for both environmental health and sustainable farming practices.

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Three-phase extraction of polysaccharide from Stropharia rugosoannulata: Process optimization, structural characterization and bioactivities

Researchers developed an efficient new method called three-phase extraction to isolate beneficial compounds called polysaccharides from wine cap mushrooms (Stropharia rugosoannulata). These polysaccharides showed strong antioxidant properties and boosted immune cell activity in laboratory tests by triggering specific cellular pathways. The findings suggest these mushroom extracts could become useful ingredients in functional foods or medicines to support immune health.

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