therapeutic action: anti-inflammatory

The Biological Activity of Ganoderma lucidum on Neurodegenerative Diseases: The Interplay between Different Active Compounds and the Pathological Hallmarks

Reishi mushroom, used in traditional Asian medicine for centuries, contains over 400 bioactive compounds that show promise in protecting the brain from degenerative diseases like Alzheimer’s and Parkinson’s. The mushroom’s components work through multiple pathways to reduce inflammation, fight oxidative stress, and protect neurons from damage. While laboratory and animal studies show encouraging results, human clinical trials are needed to confirm its effectiveness as a treatment.

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Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

This review explores how medicinal mushrooms, particularly Cerrena unicolor, can be used to improve health through functional foods and supplements. The mushroom contains natural compounds with powerful properties including fighting cancer cells, killing harmful bacteria and viruses, and protecting the body from oxidative stress. Research shows these mushrooms could be incorporated into dairy products and other foods to create innovative health-promoting products for consumers.

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Himalayan Mushrooms as a Natural Source of Ergosterol and Vitamin D2: A Review of Nutraceutical and Functional Food Perspectives

Mushrooms from the Himalayan region are naturally rich in ergosterol, a compound that converts to vitamin D2 when exposed to sunlight or UV light. This review explores how mushrooms can serve as sustainable, plant-based sources of vitamin D to address deficiencies in populations with limited sun exposure. By understanding how environmental factors and UV treatment affect ergosterol levels, scientists can develop enriched mushroom-based foods and supplements with enhanced nutritional benefits.

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Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Researchers studied how special fungal compounds called elicitors can boost the production of healing substances in a medicinal mushroom called Sanghuangporus sanghuang. By analyzing genes and metabolites, they found that adding elicitors increased beneficial compounds like betulinic acid and 2-hydroxyoleanolic acid by up to 114-fold. These findings suggest a practical way to produce more medicinal compounds from this mushroom for health applications.

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Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and shows promise as a natural antibiotic. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi by damaging their cell walls and boosting your immune system. Recent research shows it works against common infections like those caused by staph bacteria and E. coli, and may even help fight antibiotic-resistant germs.

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Structure and Bioactivity of Intracellular and Extracellular Polysaccharides of Trametes lactinea Mycelium

Researchers extracted and studied polysaccharides from Trametes lactinea mushroom mycelium grown in liquid culture. They found that these polysaccharides have strong antioxidant properties and can boost immune cell function, with the intracellular polysaccharide IP-3 showing the most promising results. These findings suggest that polysaccharides from mushroom fermentation could have potential health benefits and could be developed into medicinal supplements.

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Comparative transcriptome analyses and CRISPR/Cas9-mediated functional study of Tfsdh1 reveal insights into the interaction between Tremella fuciformis and Annulohypoxylon stygium

White wood ear fungus (Tremella fuciformis) is a popular medicinal mushroom that cannot grow on its own in nature. Researchers studied how it interacts with a companion fungus and discovered that a specific gene called Tfsdh1 is crucial for the mushroom to use sorbitol sugar and grow properly. By using advanced genetic tools to remove this gene, they showed it’s essential for the relationship between the two fungi, offering insights into how to better cultivate this nutritious mushroom.

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Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns

Scientists studied wood-decay fungi found in Central Asia’s mountains and forests, identifying 43 species that help break down wood and sometimes damage trees. These fungi have been used traditionally in medicine for various health benefits. The research used computer models to predict where these fungi are most likely to grow based on temperature, rainfall, and host plant availability, finding that they thrive best in mountainous regions where specific trees and shrubs grow.

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Antifungal efficacy of caffeic acid and nano-caffeic acid particles against candidiasis: an in vitro study

Researchers developed a nano-particle form of caffeic acid, a natural compound found in coffee and tea, to treat oral yeast infections (candidiasis). The nano-version showed better antifungal activity than regular caffeic acid, though not as strong as prescription antifungal drugs. Since it comes from plants with fewer side effects, it could offer an alternative treatment option for patients with candidiasis.

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Biodiversity-Driven Natural Products and Bioactive Metabolites

This comprehensive review explores how diverse organisms like plants, fungi, and marine creatures produce remarkable chemical compounds for survival and defense. These natural products have inspired many modern medicines, but scientists now understand that the chemical diversity comes not just from the organisms themselves but from their ecological interactions and environmental challenges. By studying how these chemicals are made and what triggers their production, researchers can discover new drugs and medicines while protecting the ecosystems that generate them.

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