anti-inflammatory – Page 17

The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

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Scientists have sequenced the complete genome of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in traditional Chinese medicine for treating parasitic infections and digestive problems. The research reveals the mushroom’s genetic blueprint, including genes responsible for producing beneficial compounds and adapting to rocky mountain environments. This foundational work aims to enable sustainable cultivation of this rare fungus and development of new medicinal treatments, addressing current conservation threats from over-harvesting.

Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

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Cordyceps militaris is a medicinal fungus used in traditional medicine for treating fatigue, boosting immunity, and fighting cancer. This review explains how growing conditions—such as the type of grain or insect substrate used, light exposure, temperature, and nutrient balance—dramatically affect the production of beneficial compounds like cordycepin. The research shows that mixing grains with insect-based materials and using specific light wavelengths can significantly increase the potency of these medicinal fungi, making them more effective for health applications.

Mushroom: an emerging source for next generation meat analogues

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Mushrooms are emerging as excellent meat substitutes because they have a meaty, chewy texture and savory flavor similar to meat, while being nutritious, low in fat, and sustainable to grow. When added to meat products like sausages, burgers, and nuggets, mushrooms improve texture, extend shelf-life, and reduce spoilage. The growing shift toward plant-based eating combined with environmental concerns makes mushroom-based meat alternatives an attractive option for consumers seeking healthier and more sustainable food choices.

Harnessing pycnidia-forming fungi for eco-friendly nanoparticle production, applications, and limitations

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Certain fungi called pycnidial fungi can create tiny particles called nanoparticles that are useful in medicine, agriculture, and environmental cleanup. These fungi naturally produce chemicals and enzymes that reduce metal ions into nanoparticles, which have antimicrobial and cancer-fighting properties. While this biological approach is more environmentally friendly than chemical methods, scientists still need to solve challenges like making it work at large scales and ensuring the nanoparticles are safe and stable.

Potential Usage of Edible Mushrooms and Their Residues to Retrieve Valuable Supplies for Industrial Applications

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Edible mushrooms are not only nutritious foods but also contain valuable compounds that are being wasted during production. Scientists are discovering new ways to use mushroom waste to make useful products like natural skincare items, water purification materials, and food additives. These innovations help reduce environmental pollution while creating valuable products, supporting a more sustainable circular economy.

Ganoderma lucidum and Robinia pseudoacacia Flower Extract Complex Alleviates Kidney Inflammation and Fibrosis by Modulating Oxidative Stress

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Researchers studied a natural supplement made from reishi mushroom and black locust flower to treat kidney disease. In laboratory and animal tests, this supplement reduced kidney damage by lowering harmful molecules called free radicals and controlling inflammation. The supplement worked by blocking specific pathways that cause kidney inflammation and scarring, suggesting it could be a helpful natural treatment for people with chronic kidney disease.

Development of dihydrooxyresveratrol-loaded nanostructured lipid carriers for safe and effective treatment of hyperpigmentation

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This research developed a new skin-brightening treatment using nanoparticles to deliver oxyresveratrol and its modified form (DHO) more effectively to the skin. The scientists improved the stability of these compounds by creating tiny lipid-based carriers that protect them from light damage and help them penetrate the skin barrier. Testing showed these formulations safely reduced melanin production without harming healthy skin cells, offering promise for cosmetic products to treat dark spots and hyperpigmentation.

Ganoderic Acid A targeting leucine-rich repeat kinase 2 involved in Parkinson’s disease–A computational study

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Researchers used computer modeling to test five compounds from Reishi mushrooms against a protein called LRRK2 that is linked to Parkinson’s disease. Ganoderic Acid A showed the strongest binding to this target protein and could potentially be developed into a treatment. The findings suggest that Reishi mushroom compounds may help protect brain cells from the degeneration seen in Parkinson’s disease and warrant further laboratory and animal testing.

The interplay between the formation of Chinese cordyceps and the characteristics of soil properties and microbial network

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This research examined how soil properties and bacteria change during the growth of Chinese cordyceps, a valuable medicinal fungus found on the Qinghai-Tibet Plateau. Scientists discovered that the most critical stage occurs when the fungus infects and consumes the host larvae, during which soil becomes less acidic, loses nutrients, and experiences significant changes in bacterial communities. The findings show that specific bacteria like Pseudomonas and Dyella help the cordyceps grow by breaking down chitin from the larvae’s exoskeleton. Understanding these interactions can help improve artificial production of this expensive medicinal fungus.

Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

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Natural plant and organism sugars called polysaccharides can improve your gut health by feeding beneficial bacteria and strengthening your intestinal barrier. These compounds help prevent diseases like obesity, diabetes, and inflammatory bowel disease by changing the types of bacteria in your gut and producing helpful substances. Polysaccharides come from common foods like mushrooms, seaweed, berries, and vegetables, making them potential natural treatments for various health conditions.

therapeutic action: anti-inflammatory