therapeutic action: anti-inflammatory

Exploring Psilocybe spp. mycelium and fruiting body chemistry for potential therapeutic compounds

This study analyzed the chemical composition of ‘magic mushrooms’ (Psilocybe) at different growth stages—liquid cultures, grain cultures, and mature fruiting bodies. Using advanced laboratory techniques, researchers found that fruiting bodies contain the highest levels of psilocybin (the psychoactive compound), while mycelium contains unique beneficial compounds like alpha-glycerylphosphorylcholine that may have therapeutic value without strong psychedelic effects. The findings suggest that Psilocybe mycelium could be developed as a non-intoxicating health supplement with potential therapeutic applications.

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Research on the Action and Mechanism of Pharmacological Components of Omphalia lapidescens

Omphalia lapidescens, a medicinal fungus used in traditional Chinese medicine, contains multiple bioactive compounds with promising health benefits. These compounds can fight parasitic infections, inhibit cancer cell growth, reduce inflammation, and provide antioxidant protection. While clinical use shows benefits especially for gastric cancer when combined with chemotherapy, more research is needed to understand how these compounds work and to improve cultivation and production methods.

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Insights into microbiome-triterpenoid correlation in Poria cocos via comparative analysis of sclerotial and soil microenvironments

Researchers discovered that the medicinal fungus Poria cocos creates its own specialized microbial environment in its underground structure that is closely linked to the production of pachymic acid, a compound with anti-cancer and immune-boosting properties. By comparing the microbes living in the fungus versus surrounding soil, they found specific beneficial bacteria and fungi that thrive in the fungus but are rare in soil. This discovery could help improve cultivation techniques to produce higher quality medicinal fungi with more therapeutic compounds.

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Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

Scientists have isolated and studied tiny capsule-like particles called extracellular vesicles from the oyster mushroom Pleurotus eryngii. These vesicles, which are naturally produced by the mushroom, contain beneficial compounds like antioxidants that help protect cells from damage. The researchers found that vesicles from mushroom mycelium (the root-like part) were of higher quality and had stronger antioxidant effects than those from the fruiting body. These findings suggest that mushroom-derived vesicles could potentially be developed into health supplements or therapeutic treatments.

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The Antioxidant Properties of Extracts of Cuscuta spp. Depend on the Parasite and the Host Species

Dodder plants (Cuscuta species) used in traditional medicine contain powerful antioxidant compounds that can help protect cells from damage. This study found that different dodder species have varying amounts of these beneficial compounds, and surprisingly, the type of host plant the dodder parasitizes directly affects how many antioxidants it produces. When dodders infect aromatic plants like thyme and rosemary, they accumulate more antioxidant compounds than when grown on other plants.

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Innovative applications of medicinal mushrooms in functional foods and nutraceuticals: a focus on health-boosting beverages

This comprehensive review explores how medicinal mushrooms are being transformed into health-boosting beverages like coffees, teas, and energy drinks. Mushrooms contain powerful compounds that support immunity, reduce inflammation, protect the liver, and enhance brain function. As consumers increasingly seek natural health alternatives, mushroom beverages are emerging as a major market trend, combining ancient wellness traditions with modern science to create convenient, tasty drinks that genuinely benefit health.

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Targeting SARS-CoV-2 with Chaga mushroom: An in silico study toward developing a natural antiviral compound

This study used computer modeling to investigate whether Chaga mushroom components can bind to and potentially block the coronavirus spike protein that SARS-CoV-2 uses to infect cells. The researchers found that three active compounds in Chaga—beta glycan, betulinic acid, and galactomannan—attached strongly to the virus’s binding sites in ways similar to known antiviral molecules. Beyond blocking viral entry, Chaga also has immune-boosting and anti-inflammatory properties that could help prevent the dangerous cytokine storm associated with severe COVID-19.

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Pigment Formation by Monascus pilosus DBM 4361 in Submerged Liquid Culture

Scientists studied how to produce natural yellow, orange, and red pigments from the fungus Monascus pilosus in liquid culture. They found that the type of sugar and nitrogen used in the fermentation significantly affects pigment production. Interestingly, glucose actually reduces pigment formation through a process called carbon catabolite repression. M. pilosus offers a safer alternative to other Monascus species because it does not produce the harmful toxin citrinin, making it suitable for use in food products.

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Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites

This study examined how different growing methods affect the medicinal compounds found in Taiwanofungus gaoligongensis, a rare Chinese medicinal fungus. Researchers discovered that growing this fungus on wood substrates from specific trees significantly increased production of beneficial compounds like antcins and antrodin C, which have anti-cancer and anti-inflammatory properties. By analyzing gene expression patterns, they identified key genes and regulatory mechanisms that control the production of these medicinal compounds, suggesting ways to improve cultivation methods for better medicinal value.

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Research Progress on Nutritional Components, Functional Active Components, and Pharmacological Properties of Floccularia luteovirens

Floccularia luteovirens is a special mushroom from the Qinghai-Tibet Plateau that has been used in traditional Tibetan medicine for centuries. It is extremely nutritious, containing as much protein as meat and numerous beneficial compounds. Scientific research shows it can help fight disease, boost immunity, and even preserve food naturally, making it promising for development as a health supplement and functional food.

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