therapeutic action: anti-inflammatory

Biosensors Based on Phenol Oxidases (Laccase, Tyrosinase, and Their Mixture) for Estimating the Total Phenolic Index in Food-Related Samples

This review discusses specialized sensors that can quickly measure the total amount of beneficial plant compounds (phenolics) in foods like tea, wine, coffee, and fruits. These biosensors use enzymes from mushrooms and other sources to detect phenolic compounds more efficiently than traditional methods. The sensors can be made more effective by using tiny materials called nanomaterials, which improve how well they work and how long they last.

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Therapeutic and Preventive Potential of Plant-Derived Antioxidant Nutraceuticals

This comprehensive review explores how compounds found in plants can protect our bodies from harmful damage caused by oxidative stress, which is linked to aging and various diseases. Plant-based foods rich in antioxidants like berries, leafy greens, and olive oil contain special molecules that can help prevent cancer, heart disease, diabetes, and other chronic conditions. The review highlights that these natural compounds work through multiple beneficial mechanisms beyond just antioxidant activity, making plant-based diets an effective strategy for maintaining health and preventing disease.

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Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

Researchers studied how adding olive mill waste to mushroom growing substrate affects the beneficial compounds in two edible mushrooms. They used advanced computer analysis of chemical data to find that this waste product increases healthy compounds like hericenones while reducing potentially harmful mycotoxins. This discovery could help make mushroom farming more sustainable and produce safer, healthier mushrooms for consumers.

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Impact of Clove Oil on Biofilm Formation in Candida albicans and Its Effects on Mice with Candida Vaginitis

This research demonstrates that clove oil, a natural and FDA-approved dietary supplement, can effectively combat Candida albicans infections that cause vaginal yeast infections. The study found that clove oil works by preventing the fungus from forming protective biofilms and by reducing inflammation. In mice with vaginal yeast infections, clove oil treatment significantly improved symptoms and reduced fungal levels, suggesting it could serve as a safer alternative to conventional antifungal medications.

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Towards engineering agaricomycete fungi for terpenoid production

Mushroom-forming fungi, particularly species like shiitake and oyster mushrooms, naturally produce valuable compounds called terpenoids used in medicines, food, and cosmetics. Scientists are learning to genetically engineer these fungi to produce even larger amounts of these beneficial compounds, potentially making them as important to biotechnology as baker’s yeast and mold have been historically. This could create new sustainable sources for medicinal compounds and industrial chemicals.

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Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

Cordyceps militaris is a medicinal fungus used in traditional medicine to treat fatigue, boost immunity, and fight disease. This comprehensive review explains how different growing conditions—including the type of food (substrate), light exposure, temperature, and nutrient ratios—affect the production of powerful healing compounds like cordycepin and polysaccharides. The review compares growing methods using grains versus insects, showing that insect-based cultivation produces higher concentrations of beneficial compounds. Key recommendations for the future include developing standardized growing protocols and integrating advanced research techniques to scale up production sustainably.

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Isolation and identification of endophytic fungi from Alhagi sparsifolia Shap. and their antibacterial activity

Researchers discovered ten types of fungi living inside the medicinal plant Alhagi sparsifolia that were never found before. Two of these fungi produced substances that killed harmful bacteria better than standard antibiotics, especially against E. coli. The researchers identified 26 different compounds in these fungi that are responsible for their antibacterial effects. This research opens new possibilities for developing natural antibacterial medicines from fungal sources.

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Haplotype-Phased Chromosome-Level Genome Assembly of Floccularia luteovirens Provides Insights into Its Taxonomy, Adaptive Evolution, and Biosynthetic Potential

Scientists successfully decoded the complete genetic blueprint of the yellow mushroom (Floccularia luteovirens), a valuable medicinal fungus found on the Tibetan Plateau. The high-quality genome assembly revealed the mushroom produces many different beneficial compounds like antitumor and anti-inflammatory molecules. The study also corrected previous scientific confusion about the mushroom’s evolutionary classification, showing it’s more closely related to other fungi than previously thought, and revealed how it adapted to harsh alpine conditions.

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Exploring the Wound Healing Potential of Hispidin

Hispidin, a natural compound from medicinal mushrooms, shows promise as a wound healing treatment. Research demonstrates that hispidin can kill harmful bacteria, stimulate skin cell growth and migration, reduce inflammation, and improve wound closure when applied as an ointment. The 5% hispidin ointment performed as well as or better than standard wound treatments in rat studies, with no toxic side effects observed, suggesting potential for future wound care products.

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