anti-inflammatory effects – Page 11

Erythema Nodosum Associated with Kerion: A Case Series and Narrative Review of the Literature

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This paper describes a rare condition where patients develop painful red bumps on the shins (erythema nodosum) as a reaction to a severe scalp fungal infection (kerion) caused by Trichophyton mentagrophytes. The authors reviewed 23 similar cases and found that this reaction usually happens during antifungal treatment and resolves within about a week. Treatment with antifungal medications like griseofulvin, sometimes combined with anti-inflammatory steroids, is effective, though scarring of the scalp may remain.

Crab vs. Mushroom: A Review of Crustacean and Fungal Chitin in Wound Treatment

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Chitin, a natural material found in crab shells and mushrooms, can be used to make wound dressings that speed up healing and fight infection. The review compares these two sources, finding that crab-derived chitin has been studied more extensively and has several commercial products available, while mushroom-derived chitin offers advantages like lower cost and easier processing. Both types work by promoting cell growth, stopping bleeding, and killing bacteria, making them promising alternatives to traditional wound dressings for treating difficult-to-heal wounds.

Synergistic target network construction and dynamic simulation analysis based on a prospective systems pharmacology strategy

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Researchers used computer-based methods to study how Sang Huang, a traditional medicinal fungus, might help treat type 2 diabetes. They identified 17 active compounds in the fungus and found that a key component called estradiol dipropionate could improve insulin sensitivity and glucose control by activating specific protein pathways. The study suggests Sang Huang could be a promising natural treatment for diabetes, though more laboratory and animal testing is needed.

Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms

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This review examines how medicinal plants can help manage nausea and vomiting caused by cancer chemotherapy. Over 22 plants including ginger, cannabis, mint, and turmeric work through multiple mechanisms like blocking serotonin pathways and reducing inflammation. Beyond reducing symptoms, these plants may also enhance chemotherapy effectiveness and boost immune function. The research suggests combining medicinal plants with standard cancer treatments could improve patient outcomes and quality of life.

Anti-Xanthine Oxidase 5′-Hydroxyhericenes A–D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol

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Researchers isolated new compounds from Lion’s mane mushroom (Hericium erinaceus) that can inhibit xanthine oxidase, an enzyme linked to breast cancer development. One compound called hericerin showed strong activity against a specific type of breast cancer cell (T47D cells) while being less harmful to normal cells. The study also corrected a misidentification from previous research, confirming that a compound previously thought to have a different structure was actually adenosine. These findings suggest Lion’s mane could be developed into a natural anti-cancer treatment.

Plant-Based Meat Analogues: Exploring Proteins, Fibers and Polyphenolic Compounds as Functional Ingredients for Future Food Solutions

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This review explores how plant-based ingredients can be used to create meat-like products that are healthier and more sustainable. By combining plant proteins, fibers, and natural compounds from fruits and vegetables, scientists are developing meat alternatives that taste and feel like real meat while offering nutritional and environmental benefits. The paper discusses which plants work best, how to extract and use these ingredients, and what challenges still need to be overcome to make these products widely available and affordable.

Research advances in fungal polysaccharides: production, extraction, characterization, properties, and their multifaceted applications

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This comprehensive review examines fungal polysaccharides, which are complex sugar molecules found in mushrooms and fungi that have powerful health benefits. Researchers describe how to grow and extract these compounds from various fungi, and explain their uses in treating diseases like cancer, reducing inflammation, and boosting immunity. The review covers different growing and extraction methods used worldwide and discusses future directions for using these natural compounds in medicine and industry.

Nuts, vegetables, fruits, and protein dietary pattern during pregnancy is inversely associated with risk of childhood allergies: a case–control study

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This study found that pregnant women who ate more nuts, vegetables, fruits, and protein had children with significantly lower rates of allergies. The research compared the diets of mothers whose children developed allergies to mothers of allergy-free children and discovered that higher consumption of omega-3 fatty acids and folic acid during pregnancy was linked to healthier immune development. The findings suggest that eating a nutrient-rich diet during pregnancy may help protect babies from developing allergies and other immune-related conditions.

Probiotics in inflammatory bowel diseases: emphasis on mechanisms and clinical application

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This review explores how probiotics (beneficial live bacteria) can help treat inflammatory bowel diseases like Crohn’s disease and ulcerative colitis. Probiotics work by restoring healthy bacteria balance in the gut, strengthening the intestinal barrier, and calming the immune system’s inflammatory response. While more research is needed, particularly for Crohn’s disease, probiotics show promise as a safe, long-term treatment option that can complement standard medications and improve patients’ quality of life.

Cerebral Hypoxia-Induced Molecular Alterations and Their Impact on the Physiology of Neurons and Dendritic Spines: A Comprehensive Review

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This review explains how low oxygen levels in the brain damage nerve cells and their connection points (dendritic spines) through a cascade of molecular changes. The brain normally has protective mechanisms, but severe or prolonged hypoxia overwhelms these defenses, leading to memory loss and cognitive problems. Several molecular pathways and supporting cells called astrocytes and microglia can help protect neurons. Understanding these protective mechanisms may lead to new treatments for brain conditions caused by low oxygen, such as stroke.

therapeutic action: anti-inflammatory effects