Anti-fatigue – mycolab.ai

Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study

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This study tests whether Ganoderma lucidum spore powder, a traditional Chinese medicine supplement, can help reduce fatigue in lung cancer patients taking the drug Osimertinib. Fatigue is a major side effect that affects most patients on this medication. The 140-patient trial compares patients receiving the supplement plus Osimertinib with those receiving a placebo plus Osimertinib, measuring fatigue levels and quality of life over 8 weeks.

Optimization of Protoplast Preparation and Establishment of PEG-Mediated Genetic Transformation Method in Cordyceps cicadae

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Scientists successfully developed a method to genetically modify Cordyceps cicadae, a valuable medicinal fungus used in traditional Chinese medicine. By optimizing how to remove the fungus’s protective cell wall and introducing new genes using a technique called PEG-mediated transformation, researchers created a stable system for genetic manipulation. This breakthrough opens the door for improving medicinal compounds in this fungus and advancing its use in treating various health conditions.

Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

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This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

Enhancement of polysaccharides production using microparticle enhanced technology by Paraisaria dubia

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Researchers developed a new method to produce medicinal polysaccharides from a Cordyceps fungus using tiny talc particles to improve fermentation. By adding the right amount and size of talc particles, they were able to produce significantly more polysaccharides with beneficial health properties. The method works well in large-scale bioreactors and could be used to produce these valuable medicinal compounds more efficiently.

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts

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Different recipes made from Ganoderma lucidum mushroom have different health benefits. This study tested two recipes in mice and found that one (PGB) was better for reducing fatigue and improving exercise performance, while the other (GBS) was better for improving sleep quality. The research shows that how you prepare and combine medicinal mushroom ingredients matters for what health benefits you get.

Isolation, identification and antibacterial activity of endophytes from the seeds of Panax japonicus

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This study investigated microscopic organisms living inside Panax japonicus seeds to understand why these seeds are difficult to grow. Researchers found the best way to clean the seeds and identified ten different microorganism species living in them. Most of these were fungi that may actually prevent seed germination, while certain bacteria species appear beneficial for plant growth and could potentially be used to improve seed cultivation in the future.

Isolation, identification and antibacterial activity of endophytes from the seeds of Panax japonicus

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Researchers isolated and identified 10 different microorganisms (7 fungi and 3 bacteria) living inside Panax japonicus seeds. They found that a specific type of bacteria (Enterobacteriaceae and Pseudomonas) may help promote seed growth, while certain fungi may inhibit it. The study also determined the best way to sterilize seeds before experimentation, which is important for studying plant propagation of this valuable medicinal herb.

Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

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Cordyceps militaris is a medicinal fungus used in traditional medicine to treat fatigue, boost immunity, and fight disease. This comprehensive review explains how different growing conditions—including the type of food (substrate), light exposure, temperature, and nutrient ratios—affect the production of powerful healing compounds like cordycepin and polysaccharides. The review compares growing methods using grains versus insects, showing that insect-based cultivation produces higher concentrations of beneficial compounds. Key recommendations for the future include developing standardized growing protocols and integrating advanced research techniques to scale up production sustainably.

Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

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Cordyceps militaris is a medicinal fungus used in traditional medicine for treating fatigue, boosting immunity, and fighting cancer. This review explains how growing conditions—such as the type of grain or insect substrate used, light exposure, temperature, and nutrient balance—dramatically affect the production of beneficial compounds like cordycepin. The research shows that mixing grains with insect-based materials and using specific light wavelengths can significantly increase the potency of these medicinal fungi, making them more effective for health applications.

Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

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This review examines how growing conditions affect the medicinal compounds produced by Cordyceps militaris mushrooms. The research shows that factors like light exposure, specific nutrient combinations, and growing on insect-based substrates can significantly boost production of beneficial compounds like cordycepin. These findings suggest ways to produce more effective and affordable medicinal mushroom products for use in supplements and pharmaceuticals.

therapeutic action: Anti-fatigue