therapeutic action: 5-flucytosine

Geographical distribution of Cryptococcus neoformans in Iran, pathogenic factors, and antifungal susceptibility profile

Researchers tested pigeon droppings from across Iran to find a dangerous fungus called Cryptococcus neoformans that can cause serious lung infections. They found this fungus in about 8.6% of samples, with more present in some provinces than others. The fungus showed concerning resistance to some common antifungal medications but remained sensitive to others like voriconazole, which could help guide treatment decisions.

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Trichosporon Urinary Tract Infections: A Hidden Menace Revealed

Trichosporon is a fungus that causes urinary tract infections primarily in hospitalized patients and those with weakened immune systems. This review found that Trichosporon asahii is the most common species responsible for these infections, especially in patients with prolonged hospital stays or using immunosuppressive medications. The drug voriconazole works best against this fungus, while some common antifungal medications like amphotericin B are less effective. Accurate identification using modern laboratory techniques is crucial for proper treatment.

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