Fungal Species:  Trametes versicolor

Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

Mushrooms are nutritious foods that contain beneficial compounds like β-glucans and polysaccharides which can help wounds heal faster. These compounds work by activating immune cells and promoting collagen production, which are essential for skin repair. Research shows that mushroom extracts from species like Ganoderma lucidum and Hericium erinaceus can accelerate wound closure in experimental models and may benefit diabetic wound care and burn treatment.

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Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways

Scientists studied how special medicinal mushroom extracts can fight advanced colon cancer in mice. They found that a blend called Agarikon Plus, especially when combined with a common chemotherapy drug, significantly improved survival rates and slowed tumor growth. By analyzing all the proteins in tumor tissues, they discovered the mushroom extracts work by disrupting the cancer cells’ ability to make proteins they need to survive and grow. This research suggests mushroom-based treatments could become important new weapons in the fight against advanced colorectal cancer.

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Solid-state fermentation as a strategy for improvement of bioactive properties of the plant-based food resources

This review explains how fermentation—a natural biological process—can enhance the health-promoting compounds in plant-based foods. By using specific fungi and bacteria on solid plant materials, scientists can increase beneficial antioxidants and proteins that may help prevent chronic diseases. This method is more environmentally friendly and cost-effective than traditional extraction techniques, making nutritious plant foods even healthier.

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The Anticancer Potential of Edible Mushrooms: A Review of Selected Species from Roztocze, Poland

This review examines edible mushrooms found in Poland’s Roztocze region for their potential to fight cancer. These mushrooms contain natural compounds like polysaccharides and proteins that can kill cancer cells in laboratory studies through various mechanisms, including triggering cell death and boosting immune function. While promising, these findings from laboratory and animal studies need further development before becoming clinical treatments.

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Bioactive Peptides and Other Immunomodulators of Mushroom Origin

Mushrooms contain special compounds called peptides and proteins that can boost your immune system and fight harmful bacteria. These mushroom-derived compounds show promise as natural alternatives to antibiotics, which are becoming less effective due to antibiotic resistance. Researchers are studying how these mushroom compounds could help treat difficult infections, wounds that won’t heal, and cancer, though more testing is needed before they can be used widely as medicines.

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Editorial: Pharmaceutically active micropollutants – how serious is the problem and is there a microbial way out?

Medicines we take don’t fully disappear—30 to 90% are excreted unchanged and end up in water supplies. These pharmaceutical residues contaminate drinking water and harm aquatic life worldwide. Scientists are discovering that certain fungi and bacteria can break down these drug residues through natural metabolic processes. By harnessing these microbes in treatment systems and improving waste management practices, we could significantly reduce pharmaceutical pollution.

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Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

This study tested 30 different mushroom species to determine which ones are the best sources of natural antioxidants that can help protect the body from damage caused by harmful free radicals. Researchers grew the mushrooms in laboratory conditions and measured their antioxidant power and beneficial compounds like polyphenols and polysaccharides. Oyster-like mushrooms called Lentinula edodes and Fomitopsis pinicola showed the strongest antioxidant activity, making them promising candidates for use in health supplements and functional foods.

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The microbial strategies for the management of chemical pesticides: A comprehensive review

Chemical pesticides used to protect crops contaminate soil and water, harming both ecosystems and human health. Scientists have discovered that specific microorganisms—bacteria, fungi, and algae—can naturally break down these harmful pesticides into harmless substances. By using advanced technologies to understand how these microbes work and even genetically enhancing them, researchers are developing sustainable solutions to clean up pesticide-contaminated environments without the toxic side effects of traditional cleanup methods.

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The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

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Hypoglycemic Properties of Leccinum scabrum Extracts—An In Vitro Study on α-Glucosidase and α-Amylase Inhibition and Metabolic Profile Determination

Researchers tested birch bolete mushrooms (Leccinum scabrum) for diabetes-fighting properties. They found that extracts from this edible mushroom were exceptionally effective at blocking enzymes that break down carbohydrates, potentially helping control blood sugar levels. The study identified key beneficial compounds including healthy fats and plant alkaloids, suggesting the mushroom could become a functional food or dietary supplement for managing type-2 diabetes.

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