Fungal Species:  Sporothrix schenckii

Disseminated subcutaneous sporotrichosis in an immunocompetent patient: A case report and a systematic literature review

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A 74-year-old man developed multiple infected lumps on his arm, wrist, and finger months after being injured by a tree branch. Doctors identified the infection as sporotrichosis caused by a fungus called Sporothrix schenckii using advanced genetic testing. He was successfully treated with itraconazole tablets for several months and completely recovered. This case is unusual because sporotrichosis typically affects people with weakened immune systems, but this patient had a normal immune system.

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Disseminated sporotrichosis caused by Sporothrix brasiliensis with testicular involvement

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This case report describes a rare fungal infection caused by Sporothrix brasiliensis in a 35-year-old man living with HIV/AIDS. The infection spread throughout his body, affecting his skin, lungs, brain, and testicles. Doctors initially thought the testicular involvement was cancer and removed the testicle, but lab tests confirmed it was a fungal infection. The patient was successfully treated with antifungal medications and remains disease-free one year later.

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Effect of Anti-Glycosphingolipid Monoclonal Antibodies in Pathogenic Fungal Growth and Differentiation. Characterization of Monoclonal Antibody MEST-3 Directed to Manpα1→3Manpα1→2IPC

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This research investigated how antibodies targeting specific sugar-containing lipids on fungal surfaces can prevent fungal growth and transformation between different forms. The findings suggest these lipids play crucial roles in fungal survival and could be targeted for new antifungal treatments. Impact on everyday life: – Could lead to new treatments for serious fungal infections – Provides better understanding of how fungi cause disease – May help develop better diagnostic tests for fungal infections – Could benefit immunocompromised patients at risk for fungal infections – Demonstrates potential for antibody-based therapies against fungi

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Extracts from Flammulina velutipes Inhibit the Adhesion of Pathogenic Fungi to Epithelial Cells

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This research investigated how extracts from the edible mushroom Flammulina velutipes could help prevent harmful fungi from attaching to human cells. The study found that these mushroom extracts can reduce the ability of disease-causing fungi to stick to human cells, potentially offering a natural way to fight fungal infections. Impacts on everyday life: • Could lead to new natural treatments for common fungal infections • Offers potential alternatives to conventional antifungal medications that may have side effects • Demonstrates the medical potential of common edible mushrooms • May help immunocompromised patients who are susceptible to fungal infections • Shows promise for developing preventive treatments against fungal diseases

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