This research investigated how combining extracts from a medicinal plant (Smilax corbularia) and a medicinal mushroom (Phellinus linteus) could potentially help fight breast cancer. The study found that these natural extracts, especially when combined in specific ratios, showed promising anti-cancer properties in laboratory tests, while potentially being less harmful to normal cells than current cancer treatments. Impacts on everyday life: • Provides evidence for the potential development of natural, less toxic cancer treatments • Supports the traditional use of medicinal plants and mushrooms in healthcare • Demonstrates how combining natural compounds may be more effective than using them individually • Offers hope for safer breast cancer treatment options in the future • Highlights the importance of continuing research into natural medicine