This research demonstrates how pomegranate peel waste can be transformed into valuable antimicrobial nanoparticles that could help fight food contamination. The study offers an environmentally friendly way to create natural food preservatives from fruit processing waste. Impacts on everyday life: • Provides a natural alternative to chemical food preservatives • Helps reduce food waste by utilizing pomegranate peels • Could lead to safer food storage and preservation methods • Offers an eco-friendly solution to combat food contamination • May help reduce the use of synthetic antimicrobial agents in food industry