Schizophyllum commune – Page 9

Chromosome-Wide Characterization of Intragenic Crossover in Shiitake Mushroom, Lentinula edodes

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This study examines how genetic material is shuffled during reproduction in shiitake mushrooms. Scientists identified 65 regions in the mushroom genome where genetic crossovers happen more frequently. They discovered that special DNA sequences and specific genes regulate where these crossovers occur. Understanding these patterns can help improve mushroom breeding programs by making it easier to combine desirable traits.

Schizophyllum commune infection following chimeric antigen receptor T-cell therapy in a patient with lymphoma

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A 71-year-old woman receiving CAR T-cell therapy for lymphoma developed a rare fungal lung infection caused by Schizophyllum commune six months after treatment. The infection presented similarly to other fungal diseases affecting the lungs and was diagnosed through bronchoscopy and fungal culture despite negative blood antibody tests. Standard antifungal medication (voriconazole) taken by mouth for four months completely resolved the infection, highlighting the need to consider rare fungi in patients receiving advanced cancer immunotherapies.

Exploring the Critical Environmental Optima and Biotechnological Prospects of Fungal Fruiting Bodies

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This research identifies the ideal growing conditions for fungal fruiting bodies like mushrooms, showing that temperature around 25°C, high humidity, and proper light exposure are key factors. The study reveals that exceeding these optimal conditions typically harms development more than staying slightly below them. Scientists discovered that fungal fruiting bodies have important uses in medicine, food production, and environmental cleanup, and new genetic technologies like CRISPR could improve cultivation methods for better yields and quality.

The Role of Nitric Oxide in the Growth and Development of Schizophyllum commune Under Anaerobic Conditions

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This study shows that nitric oxide, a chemical messenger, plays an important role in helping a wood-decay fungus called Schizophyllum commune grow and reproduce in environments without oxygen. When nitric oxide levels are boosted, the fungus grows better and can even start forming fruiting bodies (mushrooms) under low-oxygen conditions. These findings could help scientists understand how fungi survive and thrive in extreme environments like deep ocean sediments.

Natural Neuroinflammatory Modulators: Therapeutic Potential of Fungi-Derived Compounds in Selected Neurodegenerative Diseases

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This comprehensive review explores how compounds found in mushrooms could help treat serious brain diseases like Alzheimer’s and Parkinson’s disease. Mushrooms contain natural substances such as certain carbohydrates, proteins, and fats that can reduce harmful inflammation in the brain and protect nerve cells from damage. Scientists have tested these mushroom-derived compounds in laboratory and animal models, finding they can improve memory, movement, and overall brain function. This research suggests mushrooms could become an important part of new treatments for these currently incurable neurological conditions.

Fungal Sinusitis Spreading to the Sellar Region Mimicking a Pituitary Tumor: Case Report and Literature Review

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A 56-year-old woman was found to have a large mass in her sinus cavity that had eroded bone and spread to the area around her pituitary gland, mimicking a pituitary tumor. Through surgery and pathological examination, doctors discovered it was actually a fungal infection (fungus ball) rather than a tumor. This case report reviews 67 similar patients from medical literature to help doctors better recognize and treat these rare fungal infections that can threaten vision and endocrine function.

Cross-linking impacts the physical properties of mycelium leather alternatives by targeting hydroxyl groups of polysaccharides and amino groups of proteins

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Scientists have developed a leather-like material grown from mushroom mycelium (the root structure of fungi) that can match the strength of animal leather through a process called cross-linking or tanning. They tested different cross-linking chemicals—both synthetic ones like glutaraldehyde and natural plant extracts—and found that these chemicals improve the material’s strength and durability. The best results came from treating the mycelium with a low concentration of glutaraldehyde, which made it nearly as strong as real leather while using a sustainable, environmentally-friendly process.

Cell walls of filamentous fungi – challenges and opportunities for biotechnology

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Filamentous fungi like Aspergillus and Trichoderma are workhorses of the biotechnology industry, producing enzymes and pharmaceuticals worth billions annually. The cell wall surrounding these fungal cells acts as both a barrier and a filter, affecting how well proteins can be secreted into the fermentation medium. By genetically modifying cell wall components, scientists can improve enzyme production efficiency. Additionally, the billions of tons of fungal biomass left over from fermentation contain valuable chitin and chitosan that could be extracted and reused, creating a more sustainable manufacturing process.

Corrigendum: Compounds purified from edible fungi fight against chronic inflammation through oxidative stress regulation

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This article is a correction to a previous study about beneficial compounds found in edible mushrooms. The study examined how various mushroom-derived substances like polysaccharides and peptides can combat chronic inflammation by reducing oxidative stress in the body. Multiple mushroom species were analyzed for their antioxidant properties and mechanisms of action. The corrections ensure proper citation of the original research sources while maintaining the core scientific findings.

Integration of ATAC-Seq and RNA-Seq Identifies Key Genes in Light-Induced Primordia Formation of Sparassis latifolia

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Researchers studied how light triggers the formation of mushroom fruiting bodies in Sparassis latifolia using advanced molecular techniques. They identified 30 key genes that become more or less active during this light-induced transformation, particularly those involved in vitamin and amino acid metabolism. The genes identified are associated with pathways that help convert simple fungal threads into the complex mushroom structures we eat. These findings could help improve mushroom cultivation methods and deepen our understanding of how mushrooms develop.

Fungal Species: Schizophyllum commune