Schizophyllum commune – Page 7

Orthrus: a Pumilio-family gene involved in fruiting body and dark stipe development in Coprinopsis cinerea

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Scientists studied a gene called ort2 in mushrooms that controls how fruiting bodies develop, especially the long structures called dark stipes that form in darkness. They found that when this gene is active, mushrooms make more of these elongated forms, while disabling it prevents dark stipe formation. This discovery could help improve mushroom cultivation for species where these elongated forms are commercially valuable.

Transcriptional response of mushrooms to artificial sun exposure

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As climate change causes more trees to die and forest canopies to open up, mushrooms on the forest floor are exposed to more intense sun and heat. Researchers exposed Shiitake mushrooms to artificial sunlight and found that the mushrooms activate protective molecular mechanisms, particularly heat-shock proteins, to cope with the stress. This suggests that mushrooms have built-in defenses against harsh sun exposure, though scientists are not yet sure if these defenses are strong enough to protect mushroom reproduction under real-world climate change conditions.

Isolation, Characterization, and Wound-Healing Potential of β-D-Glucan from Lycoperdon pyriforme Schaeff

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Researchers isolated and studied a compound called β-D-glucan from puffball mushrooms (Lycoperdon pyriforme) that have been traditionally used to heal wounds and stop bleeding. Laboratory tests showed this compound safely promotes the movement and growth of skin cells that help wounds close without harming red blood cells, and it actually helps blood clot faster. These findings support the traditional use of this mushroom and suggest it could be developed into a new natural wound-healing treatment.

Electrical integrity and week-long oscillation in fungal mycelia

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Researchers monitored electrical signals in fungal mycelial networks over 100 days to understand how fungi coordinate their activities across space. When fungi encountered wood to decompose, they generated a clear, directional electrical signal from the wood toward the rest of the mycelium, acting like a biological command center. Most remarkably, after 60 days, the fungi developed a week-long electrical rhythm at the wood site, the longest oscillation ever recorded in fungi, which may help the fungus remember resource locations and coordinate its decomposition activities.

Tailoring the Mechanical Properties of Fungal Mycelium Mats with Material Extrusion Additive Manufacturing of PHBH and PLA Biopolymers

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Researchers have developed a new method to strengthen mushroom-based materials by using 3D printing to apply layers of plant-based plastics onto them. These reinforced materials have significantly improved strength while remaining fully biodegradable and compostable. This innovation makes fungal mycelium materials suitable for more demanding applications like flexible textiles and wearable electronics, offering a sustainable alternative to petroleum-based products.

New bioactive secondary metabolites from fungi: 2024

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Scientists discovered 907 new compounds from fungi in 2024, with most being terpenoids and polyketides that show promise as medicines. These fungal compounds demonstrate strong activity against bacteria, fungi, and inflammation, with some showing potential against cancer and diabetes. The research uses advanced techniques like genome mining and metabolomics to find these compounds more efficiently. This accelerating discovery rate suggests fungi could be a major source for developing new drugs to treat various diseases.

Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab

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A 70-year-old man developed a serious lung condition caused by a fungal infection (Schizophyllum commune) that resulted in dangerous mucus buildup and asthma attacks despite standard treatments. When traditional medications failed, doctors tried a newer biologic drug called mepolizumab that targets immune cells causing inflammation. The treatment successfully cleared the mucus, improved breathing, and allowed the patient to stop taking steroid medications while remaining symptom-free for over two years.

Misconception of Schizophyllum commune strain 20R-7-F01 origin from subseafloor sediments over 20 million years old

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Researchers questioned whether a fungus found in ancient ocean sediments 2 km below the seafloor actually came from 20 million years ago or was modern contamination. By analyzing DNA repetitive sequences in different fungal populations, they discovered the strain was genetically almost identical to modern fungi from Asia, not ancient at all. The extreme conditions in the deep sediments would make it impossible for fungi to survive or exchange genes for millions of years, proving the fungus came from surface contamination during drilling rather than ancient times.

Healthcare-associated fungal infections and emerging pathogens during the COVID-19 pandemic

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During the COVID-19 pandemic, fungal infections became a major health concern, especially in hospitalized patients. Treatments for COVID-19, such as steroids and immunosuppressive drugs, weakened patients’ immune systems, making them vulnerable to serious fungal infections like those caused by Candida auris. Current antifungal medications have significant side effects and many fungi are developing resistance, so scientists are urgently seeking safer and more effective antifungal treatments.

Saprotrophic Wood Decay Ability and Plant Cell Wall Degrading Enzyme System of the White Rot Fungus Crucibulum laeve: Secretome, Metabolome and Genome Investigations

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This study investigates how a forest fungus called Crucibulum laeve breaks down wood and plant material. Using specialized laboratory techniques, researchers found that this fungus uses a unique set of enzymes that work through oxidation (chemical breakdown using oxygen) rather than simple digestion. The fungus is particularly good at degrading birch wood and produces numerous copies of genes for these special enzymes, giving it an advantage in decomposing partially rotted plant material on the forest floor.

Fungal Species: Schizophyllum commune