Fungal Species:  Schizophyllum commune

Novel acid trehalase belonging to glycoside hydrolase family 37 from Pleurotus sp.: cloning, expression and characterization

Scientists discovered a new enzyme in Pleurotus mushrooms that breaks down trehalose, a special sugar that mushrooms use for growth and survival. This enzyme is unusual because it works in acidic conditions and belongs to a family of enzymes (GH37) that was previously thought only to contain neutral trehalases. The researchers cloned and produced this enzyme in laboratory yeast, then tested its properties to understand how it functions. This discovery helps explain how mushrooms manage their sugar metabolism during growth and decay.

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Anticancer Activity of Solvent Extracts of Hexogonia glabra against Cervical Cancer Cell Lines

Researchers tested extracts from a wild mushroom species called Hexogonia glabra against cervical cancer cells in the laboratory. The ethanolic extract was most effective, killing cancer cells by triggering apoptosis (programmed cell death) and activating genes that fight cancer. The mushroom extracts showed strong anticancer effects without harming normal cells, suggesting it could be a promising source for developing new cancer drugs.

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Evolutionary Dynamics and Functional Bifurcation of the C2H2 Gene Family in Basidiomycota

Researchers analyzed genetic instructions for zinc finger proteins across 30 species of basidiomycete fungi (including mushrooms and fungal pathogens). They found that different fungal species evolved different versions of these proteins based on their lifestyle: fungi that break down wood kept complex gene versions with lots of regulatory switches, while parasitic fungi streamlined their genes for efficiency. By studying when and where these genes are active during mushroom development, scientists discovered they orchestrate different stages from cold adaptation to mature fruiting body formation, revealing how fungi adapt to diverse ecological roles.

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Tailoring the Mechanical Properties of Fungal Mycelium Mats with Material Extrusion Additive Manufacturing of PHBH and PLA Biopolymers

Researchers developed a new way to make fungal mushroom mats stronger by printing biodegradable plastic patterns onto them using 3D printing technology. The resulting composite materials combined the sustainability of fungal products with improved strength, making them suitable for flexible applications like smart textiles and lightweight parts. Both tested polymers (PHBH and PLA) enhanced the mycelium’s mechanical properties, with PLA showing superior strength improvements while PHBH offered home compostability.

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Towards engineering agaricomycete fungi for terpenoid production

Mushroom-forming fungi, particularly species like shiitake and oyster mushrooms, naturally produce valuable compounds called terpenoids used in medicines, food, and cosmetics. Scientists are learning to genetically engineer these fungi to produce even larger amounts of these beneficial compounds, potentially making them as important to biotechnology as baker’s yeast and mold have been historically. This could create new sustainable sources for medicinal compounds and industrial chemicals.

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Strongest untreated mycelium materials produced by Schizophyllum commune dikaryons

Researchers found that mushroom mycelium grown from dikaryotic strains (with two nuclei) produces stronger, stiffer materials than traditional monokaryon strains used in mycelium-based products. These dikaryotic materials show tensile strength values comparable to some polymers, making them promising for creating sustainable alternatives to leather and textiles. The improved strength comes from differences in cell wall composition and lower expression of a hydrophobin gene, offering new possibilities for bio-based material development.

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Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

Scientists created tiny particles called zinc oxide nanoparticles using mushroom extract in an environmentally friendly way. These particles were tested and found to protect the liver from damage, kill harmful bacteria and fungi, and act as powerful antioxidants. This research suggests these mushroom-derived nanoparticles could become useful medicines for treating infections and cancer in the future.

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Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Mushrooms are nutritious superfoods packed with protein, fiber, vitamins, and minerals that support overall health. They contain special compounds that can fight inflammation, boost immunity, and help prevent serious diseases like cancer and diabetes. Beyond eating them, mushrooms are being used to make medicines, cosmetics, and animal feed, while also helping clean up polluted environments. Regular consumption of mushrooms offers significant health benefits and can be a valuable addition to any healthy diet.

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Solid-state NMR spectroscopy reveals unique properties of Trichoderma harzianum cell wall components

Scientists used advanced spectroscopy techniques to examine the cell wall structure of Trichoderma harzianum, a beneficial fungus used to protect crops from harmful fungi. They discovered that this fungus has a uniquely organized cell wall composed of tough chitin layers inside and flexible sugar polymers outside. This special arrangement helps protect the fungus from dissolving itself with its own powerful enzymes while allowing it to attack pest fungi effectively.

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Allergic bronchopulmonary mycosis caused by Scedosporium apiospermum: A case report

A 61-year-old woman developed a rare fungal infection in her lungs caused by Scedosporium apiospermum while undergoing cancer treatment. The infection caused persistent cough, mucus plugs in the airways, and high levels of immune cells called eosinophils. Doctors used genetic testing to identify the specific fungus and then treated her with corticosteroids and antifungal medications, which improved her condition significantly.

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