Fungal Species: Schizophyllum

Structural Elucidation of Heteropolysaccharides from the Peach-Shaped Dictyophora indusiata and Its Anti-Inflammatory Activity

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Researchers extracted polysaccharides from peach-shaped bamboo fungus (Dictyophora indusiata) and discovered they contain beneficial beta-glucans. When tested on human immune cells triggered to become inflamed, these polysaccharides reduced inflammatory markers and messenger proteins. The compounds were found to be chemically stable under various conditions, suggesting potential use as a natural anti-inflammatory supplement or food ingredient.

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Would global warming bring an increase of invertebrate-associated cutaneous invasive fungal infections?

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This paper discusses how invertebrate bites (from insects, spiders, and other small creatures) can transmit dangerous fungal infections to humans by directly injecting fungi into the skin. These infections are rare but serious, often causing tissue death and requiring amputation. As global warming increases temperatures, insect populations will expand into new areas, become more aggressive, and fungi may adapt to survive at higher temperatures, potentially making these infections more common and dangerous in the future.

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Characterization of the gut mycobiome in patients with non-alcoholic fatty liver disease and correlations with serum metabolome

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This study examined fungi in the gut of people with fatty liver disease and found that certain fungal species are more common in diseased patients. By analyzing both gut fungi and blood chemicals, researchers discovered that fungi significantly influence metabolic substances related to liver health. A computer model combining information about gut fungi and bacteria could identify fatty liver disease with reasonable accuracy, suggesting that fungi could be useful for disease diagnosis and potential treatment.

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Characterization of the gut mycobiome in patients with non-alcoholic fatty liver disease and correlations with serum metabolome

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This research reveals that the types of fungi living in our gut are linked to fatty liver disease in ways we didn’t fully understand before. While researchers have long studied bacteria in our gut, they largely ignored fungi, which turns out to play an important role too. The study found that certain fungal species are more common in people with fatty liver disease, and these fungi influence the metabolites (chemical compounds) in the blood that affect liver health. By combining information about fungi, bacteria, and blood chemistry, scientists developed a test that could identify fatty liver disease with 77% accuracy, suggesting that looking at gut fungi could help doctors diagnose and treat this common liver condition.

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Mushroom Bioactive Molecules as Anticancerous Agents: An Overview

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Mushrooms contain natural compounds that show promise in fighting cancer by triggering cancer cell death and boosting immune function. Different mushroom species like oyster, shiitake, and button mushrooms contain substances such as beta-glucans and other polysaccharides that have demonstrated anticancer properties in laboratory and animal studies. While these mushroom compounds work through multiple mechanisms including preventing new blood vessel formation to tumors and stopping cancer cell division, more human clinical trials are needed to confirm their effectiveness as cancer treatments.

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