Two Novel Tyrosinase Inhibitory Sesquiterpenes Induced by CuCl2 from a Marine-Derived Fungus Pestalotiopsis sp. Z233
This research discovered two new natural compounds produced by marine fungi when exposed to copper stress. These compounds showed promising ability to inhibit tyrosinase, an enzyme involved in skin pigmentation. This discovery could lead to new treatments for skin conditions involving excess pigmentation. Impacts on everyday life: • Potential development of new skin whitening or anti-pigmentation treatments • Demonstrates new ways to discover natural compounds for medical use • Advances understanding of how organisms adapt to environmental stress • Could lead to more environmentally friendly production of therapeutic compounds