Rhizopus delemar – mycolab.ai

From Nature to Design: Tailoring Pure Mycelial Materials for the Needs of Tomorrow

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Scientists are developing new materials made from mushroom mycelium that could replace leather, foam, and plastic products. These fungal-based materials grow on simple agricultural waste, are completely biodegradable, and have a much smaller environmental footprint than traditional materials. Companies like MycoWorks are already producing mycelium leather for major fashion brands, showing this technology is moving from laboratories into real products.

Solid-state NMR spectroscopy reveals unique properties of Trichoderma harzianum cell wall components

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Scientists used advanced spectroscopy techniques to examine the cell wall structure of Trichoderma harzianum, a beneficial fungus used to protect crops from harmful fungi. They discovered that this fungus has a uniquely organized cell wall composed of tough chitin layers inside and flexible sugar polymers outside. This special arrangement helps protect the fungus from dissolving itself with its own powerful enzymes while allowing it to attack pest fungi effectively.

Mycofabrication of sustainable mycelium-based leather using Talaromyces sp. and irradiated eggplant peel waste

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Scientists developed a new type of eco-friendly leather made from fungal mycelium grown on eggplant peel waste. Using radiation to treat the eggplant peels made them stronger and more flexible, and optimizing the growing conditions improved the material’s quality. The resulting mycoleather has mechanical properties comparable to real leather but is completely biodegradable and sustainable, offering a promising alternative to traditional leather production.

Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

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This research examined dangerous mold infections (Mucormycosis) that became more common after COVID-19. Scientists identified the types of molds causing these infections in Iran by testing 116 patient samples and 65 soil samples from across the country. They tested these molds against 13 different antifungal medications to find which drugs work best. The results showed that amphotericin B and posaconazole were the most effective medications, and patient samples were more susceptible to these drugs than environmental soil samples.

Revealing structure and shaping priorities in plant and fungal cell wall architecture via solid-state NMR

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This review explains how scientists use a special type of microscopy called solid-state NMR to study the protective outer layers of fungi and plants. The research shows that fungal pathogens can cleverly rearrange their cell walls to resist antifungal medicines, and that plants carefully organize their cell walls during growth by forming specific connections between different molecules. Understanding these structures at the molecular level could help develop better antifungal treatments and improve how we use plant biomass for biofuels and materials.

Cross-linking impacts the physical properties of mycelium leather alternatives by targeting hydroxyl groups of polysaccharides and amino groups of proteins

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Scientists have developed a leather-like material grown from mushroom mycelium (the root structure of fungi) that can match the strength of animal leather through a process called cross-linking or tanning. They tested different cross-linking chemicals—both synthetic ones like glutaraldehyde and natural plant extracts—and found that these chemicals improve the material’s strength and durability. The best results came from treating the mycelium with a low concentration of glutaraldehyde, which made it nearly as strong as real leather while using a sustainable, environmentally-friendly process.

Cell walls of filamentous fungi – challenges and opportunities for biotechnology

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Filamentous fungi like Aspergillus and Trichoderma are workhorses of the biotechnology industry, producing enzymes and pharmaceuticals worth billions annually. The cell wall surrounding these fungal cells acts as both a barrier and a filter, affecting how well proteins can be secreted into the fermentation medium. By genetically modifying cell wall components, scientists can improve enzyme production efficiency. Additionally, the billions of tons of fungal biomass left over from fermentation contain valuable chitin and chitosan that could be extracted and reused, creating a more sustainable manufacturing process.

Cross-linking impacts the physical properties of mycelium leather alternatives by targeting hydroxyl groups of polysaccharides and amino groups of proteins

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Scientists developed a leather-like material made from mushroom mycelium by treating it with chemical cross-linkers similar to those used in traditional leather tanning. The best results came from using glutaraldehyde, which chemically bonded to the mycelium’s proteins and carbohydrates, creating a stronger and more durable material. While the mycelium leather now has comparable strength to conventional leather, it needs to be more flexible. This research offers a more environmentally sustainable alternative to animal leather.

Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

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This study examined dangerous mold infections called mucormycosis that became more common during the COVID-19 pandemic, particularly in Iran. Researchers tested over 180 fungal samples from patients and soil to understand which types of molds cause infections and which antifungal medicines work best against them. They found that two medicines, amphotericin B and posaconazole, were most effective, while fungi from soil samples were often more resistant to treatment than those from infected patients. This research helps doctors choose the right treatments for patients with these serious infections.

Fungal Species: Rhizopus delemar