Fungal Species:  Rhizopus arrhizus

Various types of mycorrhizal fungi sequences detected in single intracellular vesicles

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Researchers discovered that single fatty droplet-like structures inside plant roots can contain genetic material from multiple types of fungi, both Glomeromycotina and Mucoromycotina. They developed new molecular tools to detect and identify these fungi without bias. This finding suggests fungi may live together more intimately than previously thought, which could help us better understand how plants get nutrients from fungal partners in soil.

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Clinical profiling, antifungal drug susceptibility, and biofilm formation ability in pulmonary mucormycosis

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This study examined 26 patients with a serious lung fungal infection called mucormycosis in a Beijing hospital. Most patients were older with health problems like diabetes and high blood pressure, and sadly about 4 in 10 died. Interestingly, most patients had other infections (viral or fungal) before developing mucormycosis. The researchers tested which antifungal drugs worked best against the fungus, finding that amphotericin B was most effective, though it can damage kidneys. They also discovered that most of the fungal strains could form protective biofilm structures, making treatment more difficult.

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Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

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This research examined dangerous mold infections (Mucormycosis) that became more common after COVID-19. Scientists identified the types of molds causing these infections in Iran by testing 116 patient samples and 65 soil samples from across the country. They tested these molds against 13 different antifungal medications to find which drugs work best. The results showed that amphotericin B and posaconazole were the most effective medications, and patient samples were more susceptible to these drugs than environmental soil samples.

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Epidemiology of mucormycosis in COVID-19 patients in northwest Iran: Rhizopus arrhizus as the predominant species

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During the COVID-19 pandemic, some patients developed a severe fungal infection called mucormycosis alongside their coronavirus infection. This study found that 63 COVID-19 patients in Iran developed mucormycosis, which primarily affected the sinuses and brain. The researchers identified that a fungus called Rhizopus arrhizus caused most infections, and patients who received corticosteroids (used to treat severe COVID-19) had a higher risk, especially those who developed diabetes from the steroids.

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Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

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This study examined dangerous mold infections called mucormycosis that became more common during the COVID-19 pandemic, particularly in Iran. Researchers tested over 180 fungal samples from patients and soil to understand which types of molds cause infections and which antifungal medicines work best against them. They found that two medicines, amphotericin B and posaconazole, were most effective, while fungi from soil samples were often more resistant to treatment than those from infected patients. This research helps doctors choose the right treatments for patients with these serious infections.

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Updates on the Taxonomy of Mucorales with an Emphasis on Clinically Important Taxa

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This research provides an updated understanding of how we classify and identify an important group of fungi called Mucorales, which can cause serious infections in humans. The findings help medical professionals better identify these fungi and understand their potential risks. Impacts on everyday life: • Improved diagnosis of fungal infections in hospitals • Better understanding of food spoilage caused by these fungi • Enhanced safety in food fermentation processes (like soy products) • More effective prevention of fungal infections in immunocompromised patients • Better quality control in biotechnology applications using these fungi

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Fungal Priming: Prepare or Perish

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This research examines how fungi can ‘remember’ and adapt to stressful conditions they’ve previously encountered, similar to how vaccines work to prepare immune systems. This ability to learn from past stress helps fungi survive better in challenging environments. Impact on everyday life: – Helps explain why some fungi become resistant to antifungal medications – Provides insights into how crop-damaging fungi adapt to agricultural fungicides – Suggests new approaches for controlling harmful fungi in agriculture and medicine – Explains how fungi are adapting to climate change – Influences food preservation and storage methods

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