Fungal Species: Pneumocystis jirovecii

Pneumocystis jirovecii is a potential pivotal ecological driver contributing to shifts in microbial equilibrium during the early-life lower airway microbiome assembly

Researchers studied how bacteria and fungi colonize infant lungs during the first year of life by examining lung tissue from autopsied infants. They found that the lung microbiome undergoes major changes between 2-4 months of age, and that a common fungal infection called Pneumocystis plays a key role in reshaping this microbial community. These early-life changes could have lasting impacts on children’s respiratory health later in life.

Read More »

Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review

This study examines rare but serious fungal infections in patients with chronic granulomatous disease, a genetic immune disorder. Researchers analyzed 122 cases of non-Aspergillus fungal infections from French hospitals and published literature, finding that these infections often occur despite preventive antifungal medications and are challenging to diagnose. The infections were found in the lungs most commonly but could spread to bones, brain, and other organs, with treatments including antifungal drugs, surgery, and in some cases bone marrow transplants.

Read More »
Scroll to Top