Fungal Species: Pleurotus eryngii

Enhancing the Substrate Adaptability of Laccase through Ancestral Sequence Reconstruction for Applications in Mycotoxin Detoxification

Researchers used evolutionary analysis to redesign a fungal enzyme called laccase to better detoxify harmful mold toxins found in grains. The new engineered enzyme (LacANC278) can break down both aflatoxin and zearalenone toxins much more effectively than the original enzyme, and converts them into less harmful substances. This enzyme works without expensive helper chemicals and works well at room temperature, making it practical for treating contaminated corn and other grains.

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Comprehensive review on oyster mushroom species (Agaricomycetes): Morphology, nutrition, cultivation and future aspects

Oyster mushrooms are increasingly popular edible fungi that can be grown on agricultural waste materials like rice and wheat straw. These nutritious mushrooms are rich in protein, vitamins, and minerals while containing compounds with health benefits including antioxidant and anti-inflammatory properties. Their cultivation offers an environmentally friendly solution to waste management while producing highly nutritious food that could help address global food security challenges.

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Functional Components from the Liquid Fermentation of Edible and Medicinal Fungi and Their Food Applications in China

Mushroom mycelium grown in liquid fermentation produces many beneficial compounds like polysaccharides and proteins that support immune function and may help fight cancer and oxidative stress. These fermented mushroom products can be added to foods, beverages, and health supplements to boost their nutritional value and health benefits. Studies show that fermented mushroom mycelium sometimes contains higher levels of beneficial compounds compared to whole mushroom fruiting bodies, making it a promising ingredient for functional foods and health products.

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The Structural Characterization and Immunomodulatory Activity of Polysaccharides from Pleurotus abieticola Fruiting Bodies

Researchers isolated and studied a polysaccharide compound from oyster mushrooms (Pleurotus abieticola) called PAPS1. When tested in mice treated with a chemotherapy drug that suppresses immunity, PAPS1 helped restore immune function by reducing harmful reactive oxygen species and boosting beneficial gut bacteria. This suggests that mushroom polysaccharides could potentially be used to help cancer patients manage the immunosuppressive side effects of chemotherapy.

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Bioactive Peptides and Other Immunomodulators of Mushroom Origin

Mushrooms contain special compounds called peptides and proteins that can boost your immune system and fight harmful bacteria. These mushroom-derived compounds show promise as natural alternatives to antibiotics, which are becoming less effective due to antibiotic resistance. Researchers are studying how these mushroom compounds could help treat difficult infections, wounds that won’t heal, and cancer, though more testing is needed before they can be used widely as medicines.

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Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

This study shows how adding olive mill waste to mushroom growing substrate can increase beneficial compounds in mushrooms while reducing harmful toxins. Researchers grew two types of edible mushrooms (lion’s mane and king oyster) on substrate containing different amounts of olive mill waste and used advanced chemical analysis to identify how the waste affected the mushrooms’ medicinal compounds. Adding olive mill waste increased healthy compounds like hericenones and erinacerins while decreasing toxic enniatin compounds, potentially creating safer and more nutritious mushrooms for consumers.

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Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

This study tested 30 different mushroom species to determine which ones are the best sources of natural antioxidants that can help protect the body from damage caused by harmful free radicals. Researchers grew the mushrooms in laboratory conditions and measured their antioxidant power and beneficial compounds like polyphenols and polysaccharides. Oyster-like mushrooms called Lentinula edodes and Fomitopsis pinicola showed the strongest antioxidant activity, making them promising candidates for use in health supplements and functional foods.

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The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

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Beneficial bacterial-Auricularia cornea interactions fostering growth enhancement identified from microbiota present in spent mushroom substrate

Researchers discovered that certain beneficial bacteria, particularly Pseudonocardia mangrovi, can significantly boost the growth of wood ear mushrooms (Auricularia cornea) through laboratory studies. By analyzing the microscopic communities in spent mushroom substrates from high-yielding versus low-yielding farms, they identified bacteria that promote mushroom growth through multiple mechanisms. Co-cultivation experiments and protein analysis revealed these bacteria work synergistically by helping mushrooms break down nutrients and produce growth-enhancing compounds. This research can help farmers select beneficial microbes to improve mushroom yields and profitability.

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Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

Researchers isolated tiny particles called extracellular vesicles (EVs) from a medicinal mushroom called king oyster mushroom (Pleurotus eryngii). These EVs act like natural delivery packages containing beneficial compounds like antioxidants and anti-inflammatory molecules. The study found that EVs from mushroom mycelium (the root-like part) were purer and more potent than those from the mushroom cap, with strong abilities to neutralize harmful free radicals in the body.

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