This research examines how natural supplements like probiotics, medicinal mushrooms, and plant extracts can help maintain a healthy gut microbiome. A balanced gut microbiome is crucial for overall health and can impact various conditions from digestive issues to mental health. Impacts on everyday life: • Better understanding of how diet and supplements can improve gut health • New natural alternatives to antibiotics for treating gut-related issues • Potential prevention strategies for common diseases through gut health maintenance • Improved options for managing digestive disorders naturally • Greater awareness of the connection between gut health and overall wellbeing