This research examines how various mushrooms can help protect and heal the liver from damage. Scientists found that many edible and medicinal mushrooms contain natural compounds that can prevent and treat liver injury. These findings are important for developing new treatments for liver diseases using natural products instead of synthetic drugs. Impacts on everyday life: • Provides scientific support for using certain mushrooms as natural liver health supplements • Offers potential alternatives to conventional medications for liver problems • Validates traditional uses of medicinal mushrooms in various cultures • Suggests new ways to prevent liver damage through diet and nutrition • Opens possibilities for developing new liver medications with fewer side effects