This article provides an annual overview of major developments in the field of mycology during 2021. It covers important organizational changes in the International Mycological Association, the launch of new initiatives like World Fungus Day, and updates on major conferences and publications. The impact on everyday life includes: • Establishment of World Fungus Day to increase public awareness of fungi’s importance in ecosystems and human life • Progress in understanding fungal diseases affecting human health, like Candida auris infections • Development of new approaches to fungal conservation and recognition of fungi alongside plants and animals • Advances in mycological knowledge through new publications and research • Changes in international mycological organization governance affecting research coordination worldwide