Fungal Species: Panaeolina

Drug–drug interactions involving classic psychedelics: A systematic review

This review examined how psychedelic drugs like LSD and psilocybin interact with other medications people might be taking. Researchers found that certain psychiatric medications like antipsychotics can block the effects of psychedelics, while other drugs may enhance them. The study highlights the importance of understanding these interactions for safe therapeutic use of psychedelics in clinical settings.

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Acute Kidney Failure and Myocarditis Triggered by Magic Mushroom Toxicity in a Patient With Prior Cocaine Exposure

A middle-aged man who used magic mushrooms along with alcohol and LSD developed severe kidney failure and heart inflammation. He had previously used cocaine, which made his condition worse by promoting blood clots throughout his body. Despite dialysis treatment, his kidneys stopped working, he developed heart problems and blood clots in major blood vessels, and he unfortunately passed away. This case highlights how dangerous it can be to mix magic mushrooms with other drugs, especially for people with a history of cocaine use.

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Exploring Psilocybe spp. mycelium and fruiting body chemistry for potential therapeutic compounds

This study compared the chemical makeup of psilocybin mushroom mycelium (the root-like growth) versus fruiting bodies (the mushrooms themselves) to understand their different therapeutic potential. While fruiting bodies contain much higher levels of psilocybin, the psychoactive compound, mycelium accumulates other beneficial compounds like α-GPC that may enhance cognition and motor function without strong psychedelic effects. This research suggests that mushroom mycelium could be developed as a non-intoxicating therapeutic alternative with its own unique health benefits.

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