This research explored the best way to grow the edible mushroom Oudemansiella canarii using different agricultural waste materials. The study found that using cottonseed hull waste as the main growing material produced the best results. This discovery has important implications for both mushroom cultivation and agricultural waste management. Impacts on everyday life: • Provides a new way to produce nutritious food from agricultural waste • Helps reduce environmental pollution from agricultural byproducts • Offers farmers additional income opportunities through mushroom cultivation • Contributes to more sustainable food production methods • Increases the availability of protein-rich food sources