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Antifungal susceptibility testing of Microsporum canis isolated from the skin of dermatologically healthy cats

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Researchers tested healthy cats in Chile and found that about 5% carried a fungus called Microsporum canis that can cause ringworm. This fungus was resistant to a common antifungal drug called fluconazole. Indoor cats were more likely to carry the fungus than outdoor cats. Because cats can spread this fungus to people, identifying carrier cats is important for preventing human infections.

Diversity and Distribution of Colletotrichum Species Causing Anthracnose in China

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Researchers identified 16 different species of Colletotrichum fungi causing anthracnose (a leaf and branch disease) in plants across five Chinese provinces. They discovered four previously unknown species and clarified the classification of several known species using DNA analysis. The study found that different regions had different predominant fungal species, with walnut being particularly susceptible to specific Colletotrichum species. These findings help understand and manage anthracnose diseases in economically important plants in China.

Protoplast-mediated transformation of Madurella mycetomatis using hygromycin resistance as a selection marker

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Scientists have successfully developed a genetic engineering method for Madurella mycetomatis, the fungus that causes mycetoma, a serious tropical disease. They used a technique to remove the fungal cell wall and insert genes into the cells, creating strains that produce green fluorescent protein (GFP). This breakthrough enables researchers to better understand how this fungus causes disease and to develop new treatments.

Biocontrol Potential of Bacillus velezensis RS65 Against Phytophthora infestans: A Sustainable Strategy for Managing Tomato Late Blight

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Researchers tested 30 soil bacteria from tomato roots to find natural disease fighters. They discovered that Bacillus velezensis RS65, a beneficial bacterium, effectively prevents tomato late blight by producing enzymes and toxins that kill the fungal pathogen. In greenhouse tests, plants treated with RS65 had half the disease severity compared to untreated plants, suggesting this bacteria could replace chemical fungicides in sustainable tomato farming.

Mechanism Analysis of Amphotericin B Controlling Postharvest Gray Mold in Table Grapes

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This research shows that amphotericin B, a natural compound produced by bacteria, can effectively prevent gray mold from spoiling table grapes after harvest. The compound works by damaging the mold’s cell membranes and also activates the grapes’ own defense systems. At a treatment level of 200 mg/L, it completely prevented mold growth on grapes over a three-day storage period, offering a safer, more environmentally friendly alternative to synthetic fungicides.

COVID-19-associated Pulmonary Aspergillosis in Mechanically Ventilated Patients at 7 US Hospitals: Epidemiology and Estimated Likelihood of Invasive Pulmonary Aspergillosis—Results of the Prospective MSG-017 Study

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A fungal infection caused by Aspergillus commonly occurs in COVID-19 patients on ventilators, affecting about 7% of cases. The study found that having this infection was linked to high death rates, but it was unclear whether the fungal infection itself or the severe COVID-19 caused the deaths. Single positive test results for the fungus are not reliable for diagnosis, and antifungal drugs did not improve survival rates.

Integrating Machine Learning and Molecular Methods for Trichophyton indotineae Identification and Resistance Profiling Using MALDI-TOF Spectra

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A new type of fungus called Trichophyton indotineae is causing stubborn skin infections that don’t respond well to standard antifungal treatments. Researchers used advanced laboratory techniques combined with computer analysis to better identify this fungus from MALDI-TOF spectra, which is a quick fingerprinting method for microorganisms. The study showed that machine learning could accurately distinguish this problematic fungus from similar species and found specific markers that could help clinics detect it faster, potentially improving patient treatment outcomes.

Rediscovery of viomellein as an antibacterial compound and identification of its biosynthetic gene cluster in dermatophytes

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Researchers discovered that dermatophytes, fungi that cause common skin infections like athlete’s foot, produce a red pigment called viomellein that kills bacteria. By studying the genes responsible for making this compound, scientists found that most dermatophytes produce it, which may help explain how these fungi establish infections on skin despite the presence of protective bacteria. This discovery opens new possibilities for understanding skin infections and potentially developing new treatments.

Inhibition of RNase to Attenuate Fungal-Manipulated Rhizosphere Microbiome and Diseases

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A fungal pathogen that causes root rot in soybeans and other crops uses a toxic protein called Fg12 to kill beneficial bacteria in the soil that would otherwise protect plants. Scientists discovered that guanosine monophosphate (GMP), a simple chemical compound, can block this toxic protein. When applied to soil, GMP protects plants by allowing beneficial bacteria to survive and fight the fungal infection.

The Prognostic Value of (1→3)-β-D-Glucan in COVID-19 Patients with and Without Secondary Fungal Disease

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During COVID-19, patients in intensive care sometimes develop dangerous fungal infections. Doctors use a blood test to measure a fungal marker called BDG to help diagnose these infections. This study found that even without confirmed fungal infection, high BDG levels predicted who would not survive, but giving antifungal medications improved survival even without proven infection.

Fungal Species: Not applicable