This research investigated compounds produced by two species of marine fungi found living in association with sea sponges. The scientists discovered a new chemical compound called paecilin E, along with several other known compounds. They tested these substances for their ability to kill harmful bacteria, particularly antibiotic-resistant strains. While most compounds were not effective, paecilin E showed promising activity against certain types of bacteria. Impacts on everyday life: – Provides new potential options for treating antibiotic-resistant bacterial infections – Demonstrates the value of marine organisms as sources of new medicines – Helps advance our understanding of natural chemical defenses in marine ecosystems – Could lead to development of new antibacterial drugs – Shows promise for addressing the growing problem of antibiotic resistance