This research identified naturally disease-resistant mushroom strains from China’s Tibetan Plateau that could help protect commercial mushroom crops from a devastating fungal disease. The study also developed new genetic tools to help breed better mushroom varieties. Impacts on everyday life: – Could lead to more disease-resistant mushroom varieties in supermarkets – May help reduce crop losses and stabilize mushroom prices for consumers – Provides tools for developing improved mushroom strains with desired traits – Helps preserve valuable wild mushroom genetic resources – Could increase sustainability of commercial mushroom farming