Mushroom tyrosinase enzyme

Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo

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This research shows that betel leaves, a traditional herb used in Asian cultures, can lighten skin pigmentation through multiple mechanisms. The extract works by reducing tyrosinase enzyme activity, activating cellular cleanup processes called autophagy, and boosting the body’s natural antioxidant defenses. In both laboratory cells and living mice exposed to UV radiation, betel leaves extract effectively reduced unwanted skin darkening, suggesting it could be developed into safe natural skin-whitening products.

Investigation of the In Vitro Antioxidant, Anticholinesterase, Antiurease, Antityrosinase, and Cytotoxic Properties of a Novel Compound: 4-Methoxy-2-(4-Methoxyphenyl)Benzo[d][1,3,2]Dioxaborole

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Scientists created a new chemical compound containing boron that showed promise as a potential medicine. The compound was effective at neutralizing harmful molecules in cells and inhibiting enzymes related to Alzheimer’s disease. Importantly, it did not damage healthy cells or kill cancer cells, suggesting it could be safe for future medical applications in treating various diseases.

Acetophenone-Based 3,4-Dihydropyrimidine-2(1H)-Thione as Potential Inhibitor of Tyrosinase and Ribonucleotide Reductase: Facile Synthesis, Crystal Structure, In-Vitro and In-Silico Investigations

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Scientists created a new chemical compound that shows promise in fighting skin cancer, particularly melanoma. The compound is seven times more effective at blocking tyrosinase, an enzyme involved in skin pigmentation and cancer growth, compared to existing drugs. Computer simulations and laboratory tests confirmed that this compound can also interfere with DNA replication processes that cancer cells depend on, suggesting it could be developed into a new cancer treatment with fewer side effects.

Fungal Species: Mushroom tyrosinase enzyme

Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo

Investigation of the In Vitro Antioxidant, Anticholinesterase, Antiurease, Antityrosinase, and Cytotoxic Properties of a Novel Compound: 4-Methoxy-2-(4-Methoxyphenyl)Benzo[d][1,3,2]Dioxaborole

Acetophenone-Based 3,4-Dihydropyrimidine-2(1H)-Thione as Potential Inhibitor of Tyrosinase and Ribonucleotide Reductase: Facile Synthesis, Crystal Structure, In-Vitro and In-Silico Investigations