This research traces the remarkable journey of statins from their discovery in fungi to their development as essential medicines for treating high cholesterol. These medications, which began as natural compounds produced by various fungi, have evolved into both natural and synthetic versions that help millions of people manage their cardiovascular health. The study explains how these drugs work, their benefits, and potential side effects. Impacts on everyday life: • Provides safe and effective treatment options for people with high cholesterol • Helps prevent heart attacks and strokes in at-risk populations • Demonstrates how natural compounds from fungi can be developed into life-saving medicines • Offers multiple medication options allowing doctors to personalize treatment based on individual patient needs • Shows the importance of continuing research into natural sources for new drug development