Fungal Species:  Microporus spp.

Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

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Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

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Determination of Antimicrobial Activity of Extracts of Indigenous Wild Mushrooms Against Pathogenic Organisms

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This research investigated how extracts from wild mushrooms could fight harmful bacteria and fungi that cause infections in humans. The study found that certain mushroom species contain compounds that can effectively kill or stop the growth of dangerous pathogens, including some that are resistant to conventional antibiotics. Impacts on everyday life: • Could lead to new antibiotics derived from natural sources to treat resistant infections • Demonstrates the untapped potential of wild mushrooms for medicine • Highlights the importance of preserving forest biodiversity for medical discoveries • Offers hope for treating infections that don’t respond to current antibiotics • Shows promise for developing new natural antimicrobial treatments

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