Fungal Species:  Lentinula edodes

Exploring the Critical Environmental Optima and Biotechnological Prospects of Fungal Fruiting Bodies

Fungal fruiting bodies like mushrooms develop best within specific environmental ranges, including proper temperature (15-27°C), humidity (80-95%), light, and nutrients. This comprehensive review identifies the exact environmental ‘sweet spots’ where mushrooms thrive and explains the biotechnological applications of these fungi in medicine, food production, and environmental cleanup. The research provides practical guidance for commercial mushroom cultivation and discusses how genetic engineering could further improve production.

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Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration

This study tested whether common and medicinal mushrooms could protect against Alzheimer’s disease by reducing harmful reactive oxygen species in brain cells. Researchers tested three mushroom types using digestive simulation to see what the body could absorb, plus key compounds made by gut bacteria. The mushroom extracts and certain bacterial metabolites successfully reduced cellular damage markers and improved behavior in disease-model worms, suggesting mushroom-rich diets may help prevent neurodegeneration.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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Isolation and characterization of edible mushroom-forming fungi from Swedish nature

Swedish researchers isolated 17 strains of wild edible mushroom-forming fungi from nature and studied how they grow at different temperatures and develop fruiting bodies. They found that commercially cultivated mushroom species grow faster and prefer warmer temperatures than wild species. Several strains successfully produced mushrooms on different growing substrates, particularly on birch pellets, with some performing better than established laboratory strains. All newly isolated strains have been preserved in a research collection for future studies and potential commercial mushroom production.

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Ergothioneine: An Antioxidative, Neuroprotective and Anti-Inflammatory Compound from Mushroom Residuals

Ergothioneine is a powerful antioxidant found mainly in mushrooms that protects brain health and reduces inflammation. Mushroom processing creates large amounts of waste like stems and leftover substrate that actually contain high levels of this beneficial compound. Scientists have developed sustainable methods to extract ergothioneine from this waste, creating opportunities for new health supplements and functional foods while reducing waste and supporting environmental sustainability.

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Comparative Transcriptome Profiles of the Response of Mycelia of the Genus Morchella to Temperature Stress: An Examination of Potential Resistance Mechanisms

Scientists studied how morel mushrooms respond to different temperatures to understand why cultivation can be unpredictable. By analyzing gene activity in mushroom mycelia (the underground filaments) at temperatures from 5°C to 30°C, they found that 15-20°C was ideal for growth. At higher temperatures, the mushrooms showed signs of stress similar to heat damage in other organisms, turning brownish and activating protective genes. This research helps mushroom farmers optimize growing conditions for better yields.

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Impact of Artemisia argyi and Stevia rebaudiana substrate composition on the nutritional quality, yield and mycelial growth of L. edodes addressing future food challenges

This study tested using wormwood and stevia plant waste as alternatives to traditional wood chips in shiitake mushroom farming. Results showed that adding up to 45% wormwood or 30% stevia to growing substrates increased both the amount and nutritional quality of mushrooms produced. This sustainable approach addresses mushroom farming’s resource shortage while potentially improving the nutritional value of the final product, making it beneficial for both food production and environmental protection.

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Mushroom By-Products as a Source of Growth Stimulation and Biochemical Composition Added-Value of Pleurotus ostreatus, Cyclocybe cylindracea, and Lentinula edodes

Researchers discovered that leftover mushroom materials from commercial cultivation can be recycled to boost the growth of edible mushroom mycelium. When mushroom waste extracts were added to growing media, they enhanced mycelial growth by up to 89.5% and increased beneficial compounds like chitin and proteins. This finding suggests a promising way to reduce mushroom farming waste while simultaneously improving the nutritional quality of cultivated mushrooms.

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Synbiotic microencapsulation of Lactiplantibacillus plantarum-lentinan for enhanced growth in broilers

Researchers developed a special protective coating for beneficial bacteria called L. plantarum mixed with lentinan from mushrooms. This mixture helps chickens grow better and stay healthier by improving their digestion and fighting harmful bacteria. When the coated bacteria reach the chicken’s intestines, they release their beneficial properties, improving growth rate and immune function without using antibiotics.

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Solid-state fermentation of hemp waste: enhancing the performance of Hermetia illucens larvae and altering the composition of hemp secondary metabolites

Researchers tested whether fermenting hemp plant waste with different mushroom types could make it a better food source for black soldier fly larvae, which produce valuable protein for animal feed. They found that different mushroom species had different effects: Ganoderma lucidum significantly increased the amount of larvae produced, while Trichoderma reesei increased beneficial cannabinoid content. Pleurotus ostreatus and Hypsizygus ulmarius removed unwanted cannabinoids from the waste. This approach offers a promising way to turn hemp waste into high-quality insect feed while controlling the levels of bioactive compounds.

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