Fungal Species:  Lentinula edodes

Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

This study tested 30 different mushroom species to determine which ones are the best sources of natural antioxidants that can help protect the body from damage caused by harmful free radicals. Researchers grew the mushrooms in laboratory conditions and measured their antioxidant power and beneficial compounds like polyphenols and polysaccharides. Oyster-like mushrooms called Lentinula edodes and Fomitopsis pinicola showed the strongest antioxidant activity, making them promising candidates for use in health supplements and functional foods.

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The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review

This systematic review examines how mushroom extracts can make chemotherapy more effective at treating cancer, particularly by helping overcome cancer cells’ resistance to drugs. Researchers found that various mushroom species contain compounds that work together with chemotherapy drugs to kill cancer cells more effectively through different cellular mechanisms. The results suggest mushroom extracts could be a promising natural complement to conventional cancer treatments, though more research is needed before they can be used clinically.

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Mechanism Underlying Ganoderma lucidum Polysaccharide Biosynthesis Regulation by the β-1,3-Glucosyltransferase Gene gl20535

Researchers studied a gene called gl20535 in the medicinal mushroom Ganoderma lucidum that controls how the fungus makes beneficial polysaccharides. When they increased this gene’s activity, the mushroom produced significantly more polysaccharides with improved composition. The gene works by controlling sugar pathways and related enzyme production, and the mushroom compensates when this gene is reduced. These findings could help improve the production of medicinal mushroom products for food and health applications.

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Benzothiazole—An Antifungal Compound Derived from Medicinal Mushroom Ganoderma lucidum against Mango Anthracnose Pathogen Colletotrichum gloeosporioides

Scientists discovered that a chemical called benzothiazole found in the medicinal mushroom Ganoderma lucidum can effectively kill the fungus that causes mango anthracnose, a major disease affecting mango crops. The research showed that this natural compound completely stops fungal growth at very low concentrations (50 ppm) and prevents spore germination. This discovery offers a promising eco-friendly alternative to synthetic fungicides that can cause environmental pollution and drug resistance.

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Harnessing mushrooms for poultry nutrition: Boosting health, immunity, and productivity

Mushrooms and mushroom stems are emerging as natural feed additives that can significantly improve poultry health, growth, and egg/meat quality while reducing the need for antibiotics. These fungi contain beneficial compounds that boost immune function, reduce harmful bacteria, and protect against cellular damage. By using mushroom byproducts that are typically discarded, farmers can create more sustainable and environmentally friendly poultry production systems while improving overall bird health and productivity.

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Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

Researchers isolated tiny particles called extracellular vesicles (EVs) from a medicinal mushroom called king oyster mushroom (Pleurotus eryngii). These EVs act like natural delivery packages containing beneficial compounds like antioxidants and anti-inflammatory molecules. The study found that EVs from mushroom mycelium (the root-like part) were purer and more potent than those from the mushroom cap, with strong abilities to neutralize harmful free radicals in the body.

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Use of Medicinal Mushrooms in Layer Ration

This review discusses how medicinal mushrooms can be added to chicken feed to improve egg production and boost chicken health, offering a natural alternative to antibiotics. Several types of mushrooms like shiitake and oyster mushrooms have been shown to increase egg quality, strengthen immunity against diseases, and reduce cholesterol in eggs. These findings support the use of mushrooms as a sustainable solution for organic egg farming without compromising production or health.

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Edible mushrooms as emerging biofactories for natural therapeutics and oral biopharmaceutical delivery

Mushrooms are emerging as natural medicine factories that can be genetically engineered to produce medications taken by mouth. Beyond their traditional use as health foods, scientists are now using advanced genetic techniques to program mushrooms to manufacture therapeutic proteins and vaccines. These engineered mushrooms can naturally package and protect these medications as they pass through the stomach, releasing them safely in the intestines for absorption. This approach offers a sustainable, affordable, and cold-chain-independent alternative to conventional injected medications.

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Substrate composition effect on the nutritional quality of Pleurotus ostreatus (MK751847) fruiting body

Researchers studied how different growing materials affect the nutritional value of oyster mushrooms. They found that mushrooms grown on palm oil waste mixed with wheat or rice bran had better nutritional quality than those grown on single materials. The best mushrooms for protein came from materials containing wheat bran, while fermented materials produced the most vitamins. This research shows how agricultural waste can be recycled into nutritious food.

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Performance of oyster mushroom (Pleurotus ostreatus) on paddy straw, water hyacinth and their combinations

This study tested different combinations of rice straw and water hyacinth (an invasive aquatic weed) as growing substrates for oyster mushrooms in Nepal. Rice straw alone produced the best mushroom yield and profit. While water hyacinth alone is not suitable as a substrate, mixing it with rice straw at a 2:1 ratio could reduce costs while helping control this problematic weed. This research provides farmers with practical guidance on sustainable mushroom cultivation methods.

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