This research reviews an important chemical reaction called the Pauson-Khand reaction and its use in synthesizing natural compounds called terpenes. These compounds are found in plants and have various medicinal properties. The reaction helps chemists build complex molecules more efficiently than traditional methods. Impacts on everyday life: – Enables more efficient production of medicines derived from natural sources – Helps develop new drug candidates for treating cancer, HIV, and inflammatory diseases – Reduces the cost and environmental impact of producing therapeutic compounds – Advances our understanding of how to make complex molecules found in nature – Could lead to new treatments for various diseases through improved synthetic methods