Fungal Species:  Inonotus hispidus

The potential of fungi in the bioremediation of pharmaceutically active compounds: a comprehensive review

Pharmaceutical drugs that we take end up in our water systems because our bodies don’t fully process them. Fungi, especially types of mushrooms, have powerful enzymes that can break down these drug residues and clean contaminated water. Scientists are studying how to use these fungi in treatment systems to remove medications from hospital wastewater and drinking water sources.

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Edible Mushrooms: A Comprehensive Review on Bioactive Compounds with Health Benefits and Processing Aspects

Mushrooms are nutrient-rich foods packed with beneficial compounds that can help prevent various diseases including cancer, heart disease, and diabetes. They contain natural antioxidants and immune-boosting substances that support overall health. Scientists are developing new extraction methods to capture these beneficial compounds more efficiently, and various cooking and processing techniques can help preserve their nutritional value for daily consumption.

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Phytochemical Analysis and Anti-Ulcer Potential of Phenolic Compounds of Inonotus nidus-pici Pilát

Researchers studied a wood mushroom called Inonotus nidus-pici to understand its healing potential. They found it contains beneficial compounds like quercetin and rosmarinic acid that act as antioxidants. When tested on rats with chemically-induced stomach ulcers, the mushroom extract provided protection similar to common ulcer medications, suggesting it could help prevent stomach damage from pain relievers.

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Biotechnological Applications of Mushrooms under the Water-Energy-Food Nexus: Crucial Aspects and Prospects from Farm to Pharmacy

Mushrooms are emerging as a powerful solution for solving global food, water, and energy challenges. Scientists are using biotechnology to produce tiny healing particles from mushrooms, clean up polluted soil and water, create renewable energy, and extract beneficial compounds for medicine and health. This review shows how integrated mushroom farming can help achieve sustainable development goals while reducing waste and supporting human wellbeing.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications

Melanin from edible mushrooms like black wood ear and reishi offers a natural, sustainable alternative to synthetic melanins with impressive health benefits. These mushroom melanins demonstrate powerful antioxidant and antibacterial properties, protect against radiation damage, and can help maintain liver health. New extraction methods using special solvents are making it easier to obtain pure melanin from mushrooms efficiently, opening doors for its use in food, cosmetics, and medicines.

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The complete mitochondrial genome of medicinally important wood-decaying fungus Tyromyces fissilis within the family Incrustoporiaceae, Polyporales

Scientists have sequenced the complete genetic blueprint of a wood-rotting mushroom called Tyromyces fissilis for the first time. This fungus is medicinally important and has the ability to break down wood and produce therapeutic compounds. By analyzing its mitochondrial genome and comparing it with related fungi, researchers found that it is most closely related to another fungus called Phlebia radiata and belongs to a previously understudied fungal family. This genetic information will help scientists better understand how these fungi are related and may lead to new medical applications.

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Extraction, physicochemical properties, and antioxidant activity of natural melanin from Auricularia heimuer fermentation

Researchers optimized a method to extract melanin, a natural black pigment, from fermented wood ear mushrooms (Auricularia heimuer). Using microwave-assisted extraction with specific pH conditions, they achieved a 0.4% yield of pure melanin. The extracted melanin showed strong antioxidant properties and could be used as a natural, safe colorant and antioxidant in food and pharmaceutical products.

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Inonotus hispidus Protects against Hyperlipidemia by Inhibiting Oxidative Stress and Inflammation through Nrf2/NF-κB Signaling in High Fat Diet Fed Mice

Inonotus hispidus is an edible mushroom that may help treat obesity and high cholesterol by reducing fat levels and inflammation in the body. In mice fed a high-fat diet, the mushroom improved cholesterol profiles, reduced liver damage, and promoted beneficial gut bacteria. The beneficial effects appear to work through activating the body’s natural antioxidant defenses and reducing inflammation-causing proteins.

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Polyphenolic Hispolon Derived from Medicinal Mushrooms of the Inonotus and Phellinus Genera Promotes Wound Healing in Hyperglycemia-Induced Impairments

Researchers tested a natural compound called hispolon, extracted from medicinal mushrooms, to see if it could help heal wounds in diabetic patients. Using both laboratory cells and diabetic rats, they found that hispolon successfully reduced cell damage caused by high blood sugar, improved wound closure, and promoted healthy tissue growth. The compound worked as well as an existing diabetic wound cream and showed no harmful side effects, suggesting it could become a new natural treatment option for diabetic wound complications.

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