Fungal Species:  Hericium erinaceus

Mycelial Beehives of HIVEOPOLIS: Designing and Building Therapeutic Inner Nest Environments for Honeybees

Scientists created experimental beehives made from living mushroom mycelium (the root structure of mushrooms) combined with 3D-printed scaffolds. These hives are designed to keep bees warmer while providing natural antimicrobial compounds that protect them from diseases. The research combines digital design technology with biology to create homes that mimic the natural tree cavities where wild honeybees live, potentially making them healthier and more resilient to climate change and diseases.

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Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review

Lion’s Mane mushroom shows promising benefits for brain health, potentially improving memory and reducing symptoms of anxiety and depression. It may help prevent cancer by triggering cancer cell death and supports digestive health by promoting beneficial gut bacteria. While generally safe, some people experience mild side effects like stomach discomfort or headaches, making it an accessible supplement for overall wellness.

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Research advances in fungal polysaccharides: production, extraction, characterization, properties, and their multifaceted applications

This comprehensive review explores how mushrooms and fungi produce special carbohydrates called polysaccharides that have remarkable health benefits. These compounds can boost the immune system, fight cancer, reduce inflammation, and act as antioxidants. The article details various methods to produce and extract these valuable compounds from fungi and discusses their practical uses in medicine, food production, and agriculture.

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Increased Rates of Supplement-Associated Oxalate Nephropathy During COVID-19 Pandemic

During the COVID-19 pandemic, more people took dietary supplements and high-dose vitamin C for health reasons. However, this study found that excessive supplement intake led to a significant increase in a kidney disease called oxalate nephropathy, where calcium oxalate crystals damage the kidneys. The good news is that when patients stopped taking these harmful supplements, their kidney function often improved, emphasizing the importance of careful supplement use.

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Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus

Hericium erinaceus, commonly known as the monkey head mushroom, contains special molecules called polysaccharides that have numerous health benefits. Researchers have found that these polysaccharides can boost immunity, lower cholesterol and blood sugar, fight tumors, reduce inflammation, and promote healthy gut bacteria. Different extraction methods and purification processes can be used to obtain these beneficial compounds, making them useful for developing health supplements and medicines.

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Fungal Strain Influences Thermal Conductivity, Hydrophobicity, Color Homogeneity, and Mold Contamination of Mycelial Composites

Scientists tested mushroom-based materials grown on hemp for use as eco-friendly insulation. They compared nine different mushroom species to see which created the best insulation with desired properties. Some materials performed as well as or better than commercial foam insulation, and they discovered a novel way to prevent mold growth by exposing developing materials to dead mold spores.

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Exploring Psilocybe spp. mycelium and fruiting body chemistry for potential therapeutic compounds

This study analyzed the chemical composition of ‘magic mushrooms’ (Psilocybe) at different growth stages—liquid cultures, grain cultures, and mature fruiting bodies. Using advanced laboratory techniques, researchers found that fruiting bodies contain the highest levels of psilocybin (the psychoactive compound), while mycelium contains unique beneficial compounds like alpha-glycerylphosphorylcholine that may have therapeutic value without strong psychedelic effects. The findings suggest that Psilocybe mycelium could be developed as a non-intoxicating health supplement with potential therapeutic applications.

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Innovative applications of medicinal mushrooms in functional foods and nutraceuticals: a focus on health-boosting beverages

This comprehensive review explores how medicinal mushrooms are being transformed into health-boosting beverages like coffees, teas, and energy drinks. Mushrooms contain powerful compounds that support immunity, reduce inflammation, protect the liver, and enhance brain function. As consumers increasingly seek natural health alternatives, mushroom beverages are emerging as a major market trend, combining ancient wellness traditions with modern science to create convenient, tasty drinks that genuinely benefit health.

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A Novel Erinacine S Derivative from Hericium erinaceus Overcomes Chemoresistance in Colorectal Cancer Cells by Enhancing TRAIL/TNFR1/DR5 Expression through Histone Acetylation

This study shows that erinacine S, a natural compound from Lion’s Mane mushrooms, can help overcome drug resistance in colorectal cancer cells. The compound works by activating pathways that trigger cancer cell death and by modifying how genes are expressed at the molecular level. In both laboratory experiments and animal models, erinacine S successfully stopped tumor growth and killed resistant cancer cells, suggesting it could be a promising natural treatment for patients with hard-to-treat colorectal cancer.

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Hericioic Acids A–G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

Researchers isolated eight new bioactive compounds from a rare European mushroom species called Hericium flagellum. These compounds showed promising ability to stimulate nerve cell growth and could potentially help treat neurodegenerative diseases like Alzheimer’s and Parkinson’s. The study demonstrates that mushroom-derived natural products may offer new therapeutic approaches for conditions affecting millions of elderly people worldwide.

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