Fungal Species:  Hericium erinaceus

Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review

Ganoderma neo-japonicum, known as purple Lingzhi, is a mushroom traditionally used by indigenous communities in Malaysia and other Asian countries to treat various health conditions. This review examines 36 scientific studies published between 1991 and 2021, showing that the mushroom contains special compounds that can fight cancer cells, lower blood sugar, reduce inflammation, and boost immunity. While laboratory studies show promising results, the mushroom still needs more clinical testing in humans before it can be widely used as a medicine.

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Chemical Characterization and In Vitro Antioxidant, Anti-Inflammatory, and Colon Cancer-Preventive Potential of a Polysaccharide Fraction from Macrolepiota procera

Researchers isolated special sugar compounds called polysaccharides from parasol mushrooms and tested their health benefits. These compounds were found to fight free radicals that damage cells, reduce inflammation in the body, and specifically kill colon cancer cells while leaving healthy cells unharmed. The study suggests that parasol mushrooms could be developed into health supplements or functional foods to help prevent cancer and improve overall health.

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Exploring the Mechanisms of Amino Acid and Bioactive Constituent Formation During Fruiting Body Development in Lyophyllum decastes by Metabolomic and Transcriptomic Analyses

This study examined how Lyophyllum decastes mushrooms develop and build up their nutritious compounds. Researchers tracked amino acids and polysaccharides across four growth stages and identified which genes control their production. The mature mushrooms contained the highest levels of beneficial compounds, with amino acids reaching 45,107.39 μg/g and polysaccharides at 13.66 mg/g. These findings help explain why these mushrooms are nutritious and suggest ways to grow them better for maximum health benefits.

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Anti-inflammatory Activity of Mycelial Extracts from Medicinal Mushrooms

This research investigated how extracts from medicinal mushrooms can reduce inflammation in cells. Scientists tested different extracts from five medicinal mushrooms and found that many of them could effectively reduce inflammatory responses, with Ganoderma lucidum showing the strongest effects. Impacts on everyday life: • Provides scientific support for traditional use of medicinal mushrooms • Suggests new natural options for treating inflammatory conditions • Could lead to development of anti-inflammatory supplements • Offers potential alternatives to synthetic anti-inflammatory drugs • May help people manage chronic inflammation-related conditions

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Array of Metabolites in Italian Hericium erinaceus Mycelium, Primordium, and Sporophore

This research analyzed the beneficial compounds found in different growth stages of the medicinal mushroom Hericium erinaceus (Lion’s Mane) from Italy. The study helps improve the production of standardized supplements by identifying which growth stages produce the most beneficial compounds. Impact on everyday life: • Better quality control for Lion’s Mane supplements • More effective natural supplements for brain health • Improved understanding of how cultivation methods affect medicinal properties • Potential for more standardized natural treatments for cognitive decline • Support for sustainable production of medicinal mushroom products

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Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds

This research review examines Lion’s Mane mushroom, a traditional Asian medicinal fungus with remarkable health benefits. The mushroom contains numerous beneficial compounds that can protect the brain, heart, liver, and kidneys while fighting inflammation and boosting immunity. Impact on everyday life: – May help improve memory and cognitive function as we age – Could provide natural support for anxiety and depression – Offers potential protection against common chronic diseases – Provides a natural way to boost immune system function – Can be easily incorporated into diet as a food supplement or ingredient

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Evaluation of the Toxicological Safety of Erinacine A-Enriched Hericium erinaceus in a 28-Day Oral Feeding Study in Sprague-Dawley Rats

This research examined the safety of lion’s mane mushroom extract enriched with a compound called erinacine A, which has potential benefits for brain health. The study found that even at high doses, the extract was safe and showed no toxic effects in rats over a 28-day period. This is important for establishing its safety for potential use in supplements and medicines. Impacts on everyday life: • Confirms the safety of lion’s mane mushroom supplements for regular consumption • Supports development of natural treatments for neurological conditions • Provides confidence for people seeking natural alternatives for brain health • Helps establish proper dosing guidelines for supplement manufacturers • Opens possibilities for new therapeutic products using this mushroom extract

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Hydrophilic Metabolite Composition of Fruiting Bodies and Mycelia of Edible Mushroom Species (Agaricomycetes)

This research compared the chemical composition of mushroom caps versus their underground root-like structures in four common edible mushrooms. The study provides important insights into the nutritional value of different mushroom parts. Impacts on everyday life: • Helps consumers understand nutritional differences between mushroom parts • Could lead to more efficient mushroom production methods • Enables better quality control of mushroom products • May result in more affordable mushroom-based supplements • Helps prevent fraud in mushroom products through chemical fingerprinting

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Classification, Structure and Mechanism of Antiviral Polysaccharides Derived from Edible and Medicinal Fungus

This research examines how certain compounds found in edible and medicinal mushrooms can help fight viral infections through multiple mechanisms. These natural compounds, called polysaccharides, work by directly attacking viruses, boosting the immune system, reducing inflammation, and improving gut health. The findings are significant for developing new antiviral treatments from natural sources. Impacts on everyday life: • Provides natural alternatives to synthetic antiviral drugs with fewer side effects • Offers potential treatments for emerging viral diseases like COVID-19 • Supports the use of medicinal mushrooms in traditional and modern medicine • Suggests ways to boost immunity through dietary mushroom consumption • Could lead to development of new antiviral supplements and medications

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Comparative Examination of the Olive Mill Wastewater Biodegradation Process by Various Wood-Rot Macrofungi

This research examined how different types of wood-decomposing fungi could help clean up toxic wastewater from olive oil production. The study found that certain fungi, especially Abortiporus biennis, can effectively break down harmful compounds in this waste through enzyme production, making it less toxic to plants and the environment. This has important real-world implications: • Provides an environmentally-friendly solution for treating olive mill waste that currently poses pollution problems • Demonstrates potential for using natural biological processes instead of harsh chemicals for waste treatment • Could help olive oil producers reduce their environmental impact while potentially creating valuable byproducts • Offers a sustainable approach that could be especially valuable for small, rural olive mills • Shows promise for developing similar fungal treatments for other types of agricultural and industrial waste

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