Fungal Species:  Ganoderma tuberculosum

Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

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Identifying the “Mushroom of Immortality”: Assessing the Ganoderma Species Composition in Commercial Reishi Products

Researchers tested 37 reishi mushroom products and kits sold in the United States and found that most were mislabeled. While products claimed to contain Ganoderma lucidum, over 93% of manufactured products actually contained Ganoderma lingzhi, a different Asian species. The study discovered that 86% of products tested contained something other than what the label claimed, which matters because different Ganoderma species have different chemical compositions and potentially different health benefits.

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Elucidating ‘Lucidum’: Distinguishing the Diverse Laccate Ganoderma Species of the United States

This research clarifies which species of the medicinal mushroom genus Ganoderma are actually present in the United States. For many years, multiple different species were incorrectly labeled as a single European species (G. lucidum). Through detailed analysis of DNA and physical characteristics, the researchers identified 12 distinct native species in the U.S., with the European species only found in two small introduced populations. This has important implications for: • Accurate identification of medicinally valuable Ganoderma species in North America • Understanding which species cause decay in different types of trees • Preventing the spread of non-native fungal species through mushroom cultivation • Proper labeling of Ganoderma products in the medicinal mushroom industry • Conservation of native North American Ganoderma species

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