Fungal Species: Ganoderma microsporum

Bioactive Peptides and Other Immunomodulators of Mushroom Origin

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Mushrooms contain special compounds called peptides and proteins that can boost your immune system and fight harmful bacteria. These mushroom-derived compounds show promise as natural alternatives to antibiotics, which are becoming less effective due to antibiotic resistance. Researchers are studying how these mushroom compounds could help treat difficult infections, wounds that won’t heal, and cancer, though more testing is needed before they can be used widely as medicines.

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Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration

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This study tested whether common and medicinal mushrooms could protect against Alzheimer’s disease by reducing harmful reactive oxygen species in brain cells. Researchers tested three mushroom types using digestive simulation to see what the body could absorb, plus key compounds made by gut bacteria. The mushroom extracts and certain bacterial metabolites successfully reduced cellular damage markers and improved behavior in disease-model worms, suggesting mushroom-rich diets may help prevent neurodegeneration.

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rFIP-GMI Suppresses IGF-1–Induced Invasion and Migration in Breast Cancer Cells via PI3K/Akt/β-Catenin Inhibition

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Researchers found that a protein from a medicinal mushroom called Ganoderma microsporum can fight aggressive breast cancer by blocking a cellular pathway that helps cancer cells spread. The protein works by stopping the activation of key molecules (PI3K and Akt) that cancer cells use to invade surrounding tissues and migrate to other parts of the body. By blocking this pathway, the mushroom protein also prevents another molecule called β-catenin from entering the cell nucleus, where it would trigger genes that promote cancer growth and spread.

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Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

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Mushrooms are nutritious superfoods packed with protein, fiber, vitamins, and minerals that support overall health. They contain special compounds that can fight inflammation, boost immunity, and help prevent serious diseases like cancer and diabetes. Beyond eating them, mushrooms are being used to make medicines, cosmetics, and animal feed, while also helping clean up polluted environments. Regular consumption of mushrooms offers significant health benefits and can be a valuable addition to any healthy diet.

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Natural Neuroinflammatory Modulators: Therapeutic Potential of Fungi-Derived Compounds in Selected Neurodegenerative Diseases

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This comprehensive review explores how compounds found in mushrooms could help treat serious brain diseases like Alzheimer’s and Parkinson’s disease. Mushrooms contain natural substances such as certain carbohydrates, proteins, and fats that can reduce harmful inflammation in the brain and protect nerve cells from damage. Scientists have tested these mushroom-derived compounds in laboratory and animal models, finding they can improve memory, movement, and overall brain function. This research suggests mushrooms could become an important part of new treatments for these currently incurable neurological conditions.

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