Fungal Species: Ganoderma lucidum

Advanced Fungal Biotechnologies in Accomplishing Sustainable Development Goals (SDGs): What Do We Know and What Comes Next?

Fungi are remarkable organisms with tremendous untapped potential for solving global challenges. They can be engineered to produce life-saving medicines like antibiotics and cholesterol-lowering drugs, create nutritious food alternatives, clean up polluted environments, and help fight climate change. As we transition to more sustainable living practices, fungi represent a natural solution that has been used for centuries but is only now being fully appreciated through modern biotechnology.

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Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Mushrooms are nutritional powerhouses packed with proteins, vitamins, minerals, and special compounds that fight disease. They can help prevent and manage serious conditions like cancer, heart disease, and diabetes while supporting overall health and immunity. Beyond the kitchen, mushrooms are being developed into medicines and cosmetic products. Growing and using mushrooms also helps the environment by creating sustainable alternatives to traditional medicines and animal feeds.

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Comparative Evaluation of Mechanical and Physical Properties of Mycelium Composite Boards Made from Lentinus sajor-caju with Various Ratios of Corn Husk and Sawdust

Researchers developed biodegradable composite boards using mushroom mycelium (Lentinus sajor-caju) grown on agricultural waste like corn husks and sawdust. By adjusting the ratio of these materials and board thickness, they created boards with properties comparable to commercial softboards and acoustic panels. These eco-friendly boards could replace synthetic materials in construction and furniture, reducing waste and pollution while maintaining good mechanical strength and sound absorption properties.

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Use of Ganoderma lucidum grown on agricultural waste to remove antibiotics from water

Researchers discovered that a type of mushroom called Ganoderma lucidum can help clean water contaminated with antibiotics. When the mushroom is grown on leftover agricultural materials like almond shells and coffee grounds, its root-like structure can remove certain antibiotics from water in just three days. This offers a cheap and sustainable way to address antibiotic pollution that contributes to antibiotic-resistant infections.

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Comparative Mitogenomics Provides Valuable Insights for the Phylogeny and New DNA Barcodes of Ganoderma

Researchers successfully sequenced the mitochondrial genomes of four commonly cultivated medicinal mushroom species in the Ganoderma genus. They identified two specific genes, atp9 and nad4L, as reliable molecular barcodes that can accurately distinguish between different Ganoderma species. These DNA barcodes serve as a universal identification tool, similar to product barcodes in supermarkets, helping to identify and classify Ganoderma species for medicinal and commercial purposes.

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Bioactive Potential of Balkan Fomes fomentarius Strains: Novel Insights into Comparative Mycochemical Composition and Antioxidant, Anti-Acetylcholinesterase, and Antiproliferative Activities

This study examines three strains of Fomes fomentarius mushroom from the Balkan region, revealing they are rich sources of beneficial compounds including polyamines and phenolic compounds. These extracts demonstrated strong antioxidant properties and potential neuroprotective effects, suggesting they could help prevent diseases related to oxidative stress and aging. The research supports the traditional use of this mushroom in folk medicine and highlights its potential as a natural supplement for health promotion.

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The Effect of Fungal Nutraceutical Supplementation on Postoperative Complications, Inflammatory Factors and Fecal Microbiota in Patients Undergoing Colorectal Cancer Surgery with Curative Intent: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Researchers tested whether a supplement made from nine different medicinal mushroom types could reduce complications after colorectal cancer surgery. While the supplement didn’t significantly reduce overall complications, it did appear to boost immune function in patients undergoing traditional surgery and favorably changed the composition of gut bacteria. The supplement was well-tolerated with no serious side effects.

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Fungal Drug Discovery for Chronic Disease: History, New Discoveries and New Approaches

This article examines how fungi have provided humanity with some of the most important medicines ever created, including penicillin, drugs that prevent organ rejection, and cholesterol-lowering statins. Many of these fungal compounds work as medicines because they target processes that are similar in both fungi and humans, helping them survive competition with other fungi while coincidentally treating human diseases. New researchers are now using modern genetic tools to discover additional fungal medicines, with several promising candidates currently being tested in clinical trials for cancer, depression, and other chronic diseases.

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Unveiling the Therapeutic Potentials of Mushroom Bioactive Compounds in Alzheimer’s Disease

Mushrooms contain special compounds that may help protect the brain from Alzheimer’s disease. Research shows that eating mushrooms regularly could reduce the risk of memory problems and cognitive decline in older adults. These compounds work by reducing brain inflammation, protecting nerve cells, and helping the brain clear out harmful proteins. While these findings are promising, more human studies are needed to confirm how effective mushrooms are as an Alzheimer’s treatment.

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Water Quality Assessment and Decolourisation of Contaminated Ex-Mining Lake Water Using Bioreactor Dye-Eating Fungus (BioDeF) System: A Real Case Study

Researchers tested a natural solution for cleaning polluted water from an old mining lake in Malaysia. They used a special fungus called Ganoderma lucidum in a system called BioDeF that acts like a sponge to remove dirt and discoloration from contaminated water. After just 48 hours, this fungus-based system removed over 90% of the water’s brown color, offering a cheap and eco-friendly alternative to traditional water cleaning methods.

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