Ganoderma lucidum – Page 3

Antioxidant and Anti-Inflammatory Properties of Mushroom-Based Food Additives and Food Fortified with Them—Current Status and Future Perspectives

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Mushrooms are nutrient-rich foods containing compounds that protect our bodies from damage and reduce inflammation. When mushrooms are processed into powders, extracts, or specially designed capsules, they can be added to ordinary foods like bread, pasta, and yogurt to make them healthier. This review shows that these mushroom-enriched foods successfully boost the antioxidant power of products, though the best results depend on how the mushrooms are prepared and which type of food they’re added to.

Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways

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Scientists studied how special medicinal mushroom extracts can fight advanced colon cancer in mice. They found that a blend called Agarikon Plus, especially when combined with a common chemotherapy drug, significantly improved survival rates and slowed tumor growth. By analyzing all the proteins in tumor tissues, they discovered the mushroom extracts work by disrupting the cancer cells’ ability to make proteins they need to survive and grow. This research suggests mushroom-based treatments could become important new weapons in the fight against advanced colorectal cancer.

Enhancing the Substrate Adaptability of Laccase through Ancestral Sequence Reconstruction for Applications in Mycotoxin Detoxification

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Researchers used evolutionary analysis to redesign a fungal enzyme called laccase to better detoxify harmful mold toxins found in grains. The new engineered enzyme (LacANC278) can break down both aflatoxin and zearalenone toxins much more effectively than the original enzyme, and converts them into less harmful substances. This enzyme works without expensive helper chemicals and works well at room temperature, making it practical for treating contaminated corn and other grains.

Analysis of Gene Regulatory Network and Transcription Factors in Different Tissues of the Stropharia rugosoannulata Fruiting Body

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Researchers analyzed the gene activity patterns across different parts of wine cap mushrooms (Stropharia rugosoannulata) to understand how the fruiting body develops. By examining gene expression in six different tissue types, they identified which genes are active in each tissue and what biological processes they control. This foundational knowledge can help improve mushroom cultivation techniques and production efficiency.

Identification of Critical Candidate Genes Controlling Monokaryon Fruiting in Flammulina filiformis Using Genetic Population Construction and Bulked Segregant Analysis Sequencing

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Scientists studied enoki mushrooms to understand how they form fruiting bodies (the edible mushroom part). They created special genetic populations and used advanced DNA sequencing to find a key gene that controls whether mushroom strains can produce fruiting bodies. This discovery helps explain how mushrooms develop and could lead to better ways to grow edible mushrooms commercially.

Functional Components from the Liquid Fermentation of Edible and Medicinal Fungi and Their Food Applications in China

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Mushroom mycelium grown in liquid fermentation produces many beneficial compounds like polysaccharides and proteins that support immune function and may help fight cancer and oxidative stress. These fermented mushroom products can be added to foods, beverages, and health supplements to boost their nutritional value and health benefits. Studies show that fermented mushroom mycelium sometimes contains higher levels of beneficial compounds compared to whole mushroom fruiting bodies, making it a promising ingredient for functional foods and health products.

Development and preliminary mechanistic analysis of compound effervescent hepatoprotective granules

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Researchers developed a new health product combining three medicinal plants to protect the liver from injury. The mixture contains effective compounds that reduce liver inflammation, fight harmful oxidative stress, and protect liver cells from damage. Studies in rats showed the product improved liver function and reduced markers of liver damage, suggesting it could be useful for preventing and treating liver injuries caused by drugs, alcohol, or toxins.

Discovering the Potential Mechanisms of Medicinal Mushrooms Antidepressant Activity: A Review

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This review explores how medicinal mushrooms may help fight depression through several natural mechanisms. These mushrooms contain compounds that boost serotonin production, reduce brain inflammation, and promote healthy neural growth. The review also discusses psilocybin from magic mushrooms as a promising rapid-acting treatment for severe depression that doesn’t respond to conventional medications.

The Anticancer Potential of Edible Mushrooms: A Review of Selected Species from Roztocze, Poland

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This review examines edible mushrooms found in Poland’s Roztocze region for their potential to fight cancer. These mushrooms contain natural compounds like polysaccharides and proteins that can kill cancer cells in laboratory studies through various mechanisms, including triggering cell death and boosting immune function. While promising, these findings from laboratory and animal studies need further development before becoming clinical treatments.

The Structural Characterization and Immunomodulatory Activity of Polysaccharides from Pleurotus abieticola Fruiting Bodies

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Researchers isolated and studied a polysaccharide compound from oyster mushrooms (Pleurotus abieticola) called PAPS1. When tested in mice treated with a chemotherapy drug that suppresses immunity, PAPS1 helped restore immune function by reducing harmful reactive oxygen species and boosting beneficial gut bacteria. This suggests that mushroom polysaccharides could potentially be used to help cancer patients manage the immunosuppressive side effects of chemotherapy.

Fungal Species: Ganoderma lucidum