Fungal Species: Ganoderma lucidum

Modulating effects of Phellinus linteus polysaccharides on antioxidant capacity, immune function, intestinal function and microbiota in lipopolysaccharide-challenged broilers

Researchers studied how a medicinal mushroom extract called Phellinus linteus polysaccharides could help broiler chickens recover from immune stress caused by bacterial toxins. The supplement improved the chickens’ growth, reduced harmful inflammatory responses, and promoted beneficial gut bacteria while reducing harmful ones. The treatment strengthened the intestinal barrier and restored the chickens’ natural antioxidant defenses. This suggests the mushroom supplement could be a natural alternative to antibiotics for improving poultry health on farms.

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Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

Scientists are developing environmentally friendly ways to make silver nanoparticles using bacteria and fungi instead of harsh chemicals. These tiny particles show promise in fighting infections, treating cancer, cleaning water, and protecting crops. The review compares how bacteria and fungi each produce these particles and explains how different conditions affect their properties and effectiveness.

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The Effects of the Substrate Length and Cultivation Time on the Physical and Mechanical Properties of Mycelium-Based Cushioning Materials from Salix psammophila and Peanut Straw

Researchers developed eco-friendly cushioning materials by growing mushroom mycelium (fungal networks) on agricultural waste like willow and peanut straw. These materials match the performance of plastic foam used in packaging but are completely biodegradable and made from renewable resources. By adjusting how long the mushrooms grow and the size of the substrate pieces, scientists can control the final product’s strength, flexibility, and water resistance.

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Natural Neuroinflammatory Modulators: Therapeutic Potential of Fungi-Derived Compounds in Selected Neurodegenerative Diseases

This comprehensive review explores how compounds found in mushrooms could help treat serious brain diseases like Alzheimer’s and Parkinson’s disease. Mushrooms contain natural substances such as certain carbohydrates, proteins, and fats that can reduce harmful inflammation in the brain and protect nerve cells from damage. Scientists have tested these mushroom-derived compounds in laboratory and animal models, finding they can improve memory, movement, and overall brain function. This research suggests mushrooms could become an important part of new treatments for these currently incurable neurological conditions.

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The complete mitochondrial genome of medicinal fungus Taiwanofungus camphoratus reveals gene rearrangements and intron dynamics of Polyporales

Scientists have decoded the complete genetic blueprint of the mitochondria in Taiwanofungus camphoratus, a highly valued medicinal mushroom from Taiwan. This fungus has been used in traditional medicine for treating inflammation, cancer, and liver diseases. By comparing its mitochondrial DNA with related fungal species, researchers discovered that this mushroom has a unique genetic arrangement and uncovered how genes have been rearranged during evolution. This discovery helps scientists better understand how this important medicinal fungus evolved and can improve its classification and medical applications.

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Comparative transcriptome analysis reveals the genetic basis underlying the biosynthesis of polysaccharides in Hericium erinaceus

Researchers studied six different strains of lion’s mane mushrooms to understand how they produce beneficial compounds called polysaccharides. Using advanced genetic analysis, they identified thirteen key genes responsible for making these health-promoting molecules. The study found that a strain called PZH-05 produced the most polysaccharides, and its genes were more active than in other strains. This research helps explain why lion’s mane mushrooms are effective for boosting immunity, fighting cancer, and managing blood sugar.

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3D printed gyroid scaffolds enabling strong and thermally insulating mycelium-bound composites for greener infrastructures

Scientists developed a new eco-friendly building material by growing mushroom mycelium on specially designed 3D-printed scaffolds made from wood and plant-based plastic. These mycelium bricks are stronger, better insulators, and more fire-resistant than traditional bricks or foam insulation, while being completely biodegradable. This breakthrough could help reduce the construction industry’s massive carbon footprint and provide a sustainable alternative to harmful conventional building materials.

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Enhanced biodegradation of fluorinated pharmaceutical by Aspergillus flavus and Cunninghamella elegans biofilms: kinetics and mechanisms

This study demonstrates that two types of fungi, Aspergillus flavus and Cunninghamella elegans, can effectively remove persistent pharmaceutical pollution from wastewater when grown as biofilms on foam carriers. The fungi achieved removal rates of 92-98% for three common medications (atorvastatin, ciprofloxacin, and fluoxetine) much faster than previously reported methods. Unlike traditional fungal treatments that depend on lignin, these fungi can work in diverse environments, making them practical for wastewater treatment plants and offering a sustainable biological solution to pharmaceutical pollution.

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Integration of ATAC-Seq and RNA-Seq Identifies Key Genes in Light-Induced Primordia Formation of Sparassis latifolia

Researchers studied how light triggers the formation of mushroom fruiting bodies in Sparassis latifolia using advanced molecular techniques. They identified 30 key genes that become more or less active during this light-induced transformation, particularly those involved in vitamin and amino acid metabolism. The genes identified are associated with pathways that help convert simple fungal threads into the complex mushroom structures we eat. These findings could help improve mushroom cultivation methods and deepen our understanding of how mushrooms develop.

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Enhancement and Mechanism of Ergosterol Biosynthesis in Termite Ball Fungus Athelia termitophila by Methyl Jasmonate

Scientists studied how to increase ergosterol production in termite ball fungus, a medicinal fungus used in traditional medicine. By adding methyl jasmonate, a natural signaling molecule, they more than doubled ergosterol content. Ergosterol is used to make vitamin D2 and certain medications for inflammation and cancer. The study identified which genes need to be activated for better ergosterol production, providing insights for creating more effective medical products from fungi.

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