Ganoderma lucidum – Page 2

Screening of a Fraction with Higher Amyloid β Aggregation Inhibitory Activity from a Library Containing 210 Mushroom Extracts Using a Microliter-Scale High-Throughput Screening System with Quantum Dot Imaging

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Researchers screened 210 mushroom species from Japan to find those that could prevent harmful protein clumping in the brain associated with Alzheimer’s disease. They identified a purified fraction from the mushroom Elfvingia applanata that was more effective than a known anti-Alzheimer’s compound at stopping these protein clumps from forming. The extract also protected nerve cells from damage in laboratory tests. This finding suggests mushrooms could potentially be developed into a functional food to help prevent Alzheimer’s disease.

The Possibility of Using Sulphur Shelf Fungus (Laetiporus sulphureus) in the Food Industry and in Medicine—A Review

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Sulphur shelf fungus, known as ‘chicken of the woods,’ is a bright yellow mushroom that grows on tree trunks and has remarkable health benefits. Research shows it contains compounds with antioxidant, antibacterial, and anticancer properties, making it valuable for both food and medicine. The fungus can be cultivated relatively quickly and easily, and some countries already recognize it as safe for food use, potentially opening new applications in the food and pharmaceutical industries.

A Review on the Structure and Anti-Diabetic (Type 2) Functions of β-Glucans

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β-glucans are special sugar molecules found in foods like mushrooms, oats, and barley that can help control type 2 diabetes. These molecules work by two main methods: slowing down how quickly nutrients are absorbed in the digestive system, and blocking enzymes that break down carbohydrates into sugars. The shape and size of β-glucan molecules are very important—different structures have different effects on blood sugar control.

Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

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This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

BioKnit: development of mycelium paste for use with permanent textile formwork

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Researchers developed a new type of injectable mycelium paste combined with knitted fabric formwork to create lightweight, sustainable building materials. The BioKnit prototype demonstrates that this approach can produce large, complex structures like an arched dome using fungal material instead of traditional construction materials. The textile framework dramatically strengthens the mycelium composite while keeping the material environmentally friendly and relatively easy to produce.

Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

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Mushrooms are nutritious foods that contain beneficial compounds like β-glucans and polysaccharides which can help wounds heal faster. These compounds work by activating immune cells and promoting collagen production, which are essential for skin repair. Research shows that mushroom extracts from species like Ganoderma lucidum and Hericium erinaceus can accelerate wound closure in experimental models and may benefit diabetic wound care and burn treatment.

Integration of Physiological, Transcriptomic and Metabolomic Reveals Molecular Mechanism of Paraisaria dubia Response to Zn2+ Stress

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This research shows that a fungus called Paraisaria dubia can effectively clean up zinc pollution by removing 60% of zinc from contaminated environments. The fungus uses multiple survival strategies when exposed to zinc stress, including producing more protective slime-like substances on its surface and generating spores that are more resistant to harmful conditions. By studying the fungus at the molecular level, scientists discovered which genes and chemical compounds activate these protective responses, paving the way for using fungi as natural cleaners for heavy metal-contaminated soil and water.

Polysaccharides from Spores of Cordyceps cicadae Protect against Cyclophosphamide-Induced Immunosuppression and Oxidative Stress in Mice

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Researchers extracted and studied special compounds called polysaccharides from the spores of Cordyceps cicadae, a medicinal fungus used in traditional Chinese medicine. When tested in mice treated with a cancer drug that suppresses immunity, one of these purified compounds (CCSP-2) successfully restored immune function and reduced harmful oxidative stress. The compound works by boosting the activity of immune cells and protecting the body’s natural antioxidant defense systems, suggesting it could potentially help cancer patients manage chemotherapy side effects.

Fatty acid synthesis: A critical factor determining mycelial growth rate in Pleurotus tuoliensis

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Researchers studied why Pleurotus tuoliensis mushrooms grow slowly compared to other oyster mushroom species. They found that a key enzyme called acetyl-CoA carboxylase, which controls fat production in the mushroom cells, directly affects how fast the mycelium grows. By increasing this enzyme’s activity and providing nutrients that help fat-making, scientists were able to boost mycelial growth rates significantly, offering new strategies to improve commercial cultivation of these delicious mushrooms.

Mechanical properties of dense mycelium-bound composites under accelerated tropical weathering conditions

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Researchers developed a sustainable alternative to traditional particleboard using mushroom mycelium (fungal root structure) grown on agricultural waste like sawdust and palm fruit remnants. When exposed to hot, humid tropical conditions for 35 days, the material’s strength decreased significantly, but applying a protective oil coating helped preserve tensile strength. The study shows that with improvements to manufacturing processes, these mushroom-based composites could replace harmful formaldehyde-based particleboards in indoor construction.

Fungal Species: Ganoderma lucidum