Fungal Species: Ganoderma lucidum

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts

Different recipes made from Ganoderma lucidum mushroom have different health benefits. This study tested two recipes in mice and found that one (PGB) was better for reducing fatigue and improving exercise performance, while the other (GBS) was better for improving sleep quality. The research shows that how you prepare and combine medicinal mushroom ingredients matters for what health benefits you get.

Read More »

The application of laccase-rich extract of spent mushroom substrates for removing lignin from jute fabric waste: a dual management approach

This research shows how leftover mushroom growing material (SMS) can be recycled into a useful enzyme called laccase to make jute fabric softer and lighter by removing tough lignin components. Instead of using harsh chemicals, the scientists used mild conditions and natural enzymes to process jute waste sustainably. From just one bag of mushroom waste, they could treat an area of fabric equivalent to 2000 square meters, making this an economically attractive solution for both mushroom and textile waste management.

Read More »

Dynamic changes of nutrients, isoflavone composition and antioxidant activities during liquid-state fermentation of soybean embryo homogenate by Ganoderma lucidum

Researchers fermented soybean embryo using Ganoderma lucidum mushroom to create a more nutritious and better-tasting food product. During fermentation, the mushroom’s enzymes broke down hard-to-digest compounds and converted isoflavones into more absorbable forms while dramatically increasing antioxidant activity. The fermented product showed 8-fold higher antioxidant power and reduced unpleasant flavors, making soybean embryo a viable functional food ingredient.

Read More »

Phylogenetic Analysis and Nutritional Evaluation of Laetiporus Species in Korea

Researchers in Korea identified that ‘chicken of the woods’ mushrooms growing in the region are actually two specific species: Laetiporus versisporus and Laetiporus cremeiporus, not the species previously thought. These mushrooms are nutritionally impressive, containing substantial protein (9-18% depending on species) and high levels of beneficial β-glucans (15-35%), making them promising candidates as sustainable meat alternatives and functional food ingredients.

Read More »

Evaluation of Anticancer Potential of Ganoderma lucidum on MCF-7 Breast Cancer Cells Through Genetic Transcription of Energy Metabolism

Researchers tested extracts from Ganoderma lucidum (Reishi mushroom) against breast cancer cells in the laboratory. They found that the methanol extract was particularly effective at killing cancer cells while leaving healthy cells relatively unharmed. The mushroom works by disrupting the cancer cells’ metabolism and triggering programmed cell death, making it a promising natural treatment option that could complement conventional cancer therapies.

Read More »

Functional Approaches to Discover New Compounds via Enzymatic Modification: Predicted Data Mining Approach and Biotransformation-Guided Purification

Scientists are developing faster ways to discover new medicines from plants using two innovative methods. The first approach uses computer programs to predict which plant compounds can be chemically modified by enzymes to create new medicines with better properties. The second approach combines enzyme chemistry with traditional purification to directly isolate these modified compounds from plant extracts. These methods have successfully created new compounds with improved effectiveness against diseases like diabetes and cancer, often with much better solubility for medical use.

Read More »

From natural laboratory to drug discovery: Chemical structures, bioactivities, and biosynthesis of meroterpenoids from Ganoderma species

This review examines special compounds called meroterpenoids found in Ganoderma mushrooms (commonly known as Reishi). Scientists have identified over 350 of these compounds from 14 different Ganoderma species. These compounds show promise for treating various health conditions including cancer, kidney disease, diabetes, and inflammatory disorders. The researchers also propose how these compounds are made inside the mushroom, which could help scientists produce them more efficiently for medical use.

Read More »

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

Read More »

Green-Synthesized Nanomaterials from Edible and Medicinal Mushrooms: A Sustainable Strategy Against Antimicrobial Resistance

Scientists are developing a new weapon against antibiotic-resistant bacteria using mushrooms. These special nanoparticles derived from edible and medicinal mushrooms can kill harmful bacteria in multiple ways without the toxic chemicals used in traditional manufacturing. The nanoparticles work by disrupting bacterial membranes, creating harmful molecules called free radicals, and even boosting your body’s natural immune response. This environmentally friendly approach could become an important tool in fighting dangerous infections that don’t respond to current antibiotics.

Read More »

rFIP-GMI Suppresses IGF-1–Induced Invasion and Migration in Breast Cancer Cells via PI3K/Akt/β-Catenin Inhibition

Researchers found that a protein from a medicinal mushroom called Ganoderma microsporum can fight aggressive breast cancer by blocking a cellular pathway that helps cancer cells spread. The protein works by stopping the activation of key molecules (PI3K and Akt) that cancer cells use to invade surrounding tissues and migrate to other parts of the body. By blocking this pathway, the mushroom protein also prevents another molecule called β-catenin from entering the cell nucleus, where it would trigger genes that promote cancer growth and spread.

Read More »
Scroll to Top