Ganoderma lucidum – Page 13

Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

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This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

Development and characterization of novelly grown fire-resistant fungal fibers

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Scientists developed fire-resistant fibers from fungal mycelium grown with silica, offering a natural alternative to synthetic plastic fibers used in concrete. These fungal fibers burn more slowly, retain more material after heating, and create protective char layers that help prevent concrete spalling during fires. The new fibers are more environmentally friendly, cheaper to produce, and significantly outperform traditional polypropylene fibers in fire-resistant applications.

Biologically active secondary metabolites from white-rot fungi

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White-rot fungi are special mushrooms that can break down wood and produce unique chemical compounds with amazing health benefits. These compounds have been found to fight cancer, kill harmful bacteria, reduce inflammation, and protect nerve cells. Scientists are excited about using these natural fungal compounds to create new medicines and treat various diseases in the future.

Evaluation of Two Different Treatments for Larch Logs as Substrates to Cultivate Ganoderma tsugae in the Forest

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This study compared growing the medicinal mushroom Ganoderma tsugae on sterilized versus non-sterilized larch wood in a forest setting. Researchers found that non-sterilized wood actually produced mushrooms with higher levels of beneficial compounds like triterpenoids and polysaccharides, while requiring less processing and cost. These findings suggest that farmers can use a simpler, less expensive cultivation method while still producing high-quality medicinal mushrooms.

Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles

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Periodontitis is a serious gum disease that causes tooth loss and affects overall health. This review examines how polysaccharides (complex carbohydrates) from plants and fungi can help treat periodontitis by reducing inflammation, fighting bacteria, and helping gum tissue repair. These natural compounds work through multiple biological pathways to improve oral health outcomes while avoiding the side effects and resistance problems associated with conventional drugs.

Bioactivity and toxicity of polysaccharides derived from the phytopathogenic mushroom Ganoderma orbiforme cultured in a bioreactor

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Scientists studied a mushroom called Ganoderma orbiforme that normally harms oil palm trees to see if it could be useful as medicine. They grew the mushroom in a special bioreactor and extracted beneficial substances called polysaccharides. These substances showed promise as natural antibiotics and antioxidants while being safe for use based on safety testing with fish embryos.

Solid-state fermentation of hemp waste: enhancing the performance of Hermetia illucens larvae and altering the composition of hemp secondary metabolites

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Researchers tested whether fermenting hemp plant waste with different mushroom types could make it a better food source for black soldier fly larvae, which produce valuable protein for animal feed. They found that different mushroom species had different effects: Ganoderma lucidum significantly increased the amount of larvae produced, while Trichoderma reesei increased beneficial cannabinoid content. Pleurotus ostreatus and Hypsizygus ulmarius removed unwanted cannabinoids from the waste. This approach offers a promising way to turn hemp waste into high-quality insect feed while controlling the levels of bioactive compounds.

Screening and identifying natural products with SARS-CoV-2 infection inhibitory activity from medicinal fungi

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Researchers screened 167 extracts from 36 medicinal fungi to find natural compounds that could fight COVID-19. They discovered that certain fungi, particularly Inonotus obliquus and Pholiota adiposa, contain polysaccharides that effectively block the virus from infecting cells. These natural compounds showed promise as potential safe alternatives for developing new COVID-19 treatments and may have applications against other viral diseases.

Enhancement of polysaccharides production using microparticle enhanced technology by Paraisaria dubia

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Researchers developed a new method to produce medicinal polysaccharides from a Cordyceps fungus using tiny talc particles to improve fermentation. By adding the right amount and size of talc particles, they were able to produce significantly more polysaccharides with beneficial health properties. The method works well in large-scale bioreactors and could be used to produce these valuable medicinal compounds more efficiently.

Challenges and Opportunities in Scaling up Architectural Applications of Mycelium-Based Materials with Digital Fabrication

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Mycelium, the root structure of fungi, can be grown with agricultural waste to create building materials that are environmentally friendly and biodegradable. While these materials show promise for insulation and non-structural uses, scaling them up for large buildings faces challenges including lower strength compared to traditional materials and lack of standardized production methods. The paper reviews various fabrication techniques and existing projects to suggest how digital design and advanced manufacturing could help overcome these barriers.

Fungal Species: Ganoderma lucidum