Ganoderma lucidum – Page 12

The protecting role of Ganoderma lucidum polysaccharides on the retinal neurovascular units in rats with retinal ischemia-reperfusion injury

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This research demonstrates that polysaccharides extracted from Ganoderma lucidum mushrooms can protect rat retinas from damage caused by blocked and then restored blood flow. The treatment reduced cell death, decreased harmful oxidative stress, reduced inflammation-like responses from support cells, and improved retinal electrical function. These findings suggest that Ganoderma lucidum could potentially be developed as a therapeutic option for eye diseases like glaucoma and diabetic retinopathy where blood flow to the retina is compromised.

Mushroom-Based Supplements in Italy: Let’s Open Pandora’s Box

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Researchers tested 19 mushroom supplement products sold in Italy and found serious quality problems. Many supplements didn’t actually contain the mushroom species listed on their labels. Some products also contained toxic substances or inconsistent amounts of beneficial compounds. The study highlights the need for better regulation and manufacturing standards to ensure these popular health products are safe and effective.

From Nature to Design: Tailoring Pure Mycelial Materials for the Needs of Tomorrow

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Scientists are developing new materials made from mushroom mycelium that could replace leather, foam, and plastic products. These fungal-based materials grow on simple agricultural waste, are completely biodegradable, and have a much smaller environmental footprint than traditional materials. Companies like MycoWorks are already producing mycelium leather for major fashion brands, showing this technology is moving from laboratories into real products.

Turning the Cocopith Waste into Myceliated Biocomposite to Make an Insulator

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Researchers developed an environmentally-friendly insulation material by growing mushroom mycelium (Ganoderma lucidum) on cocopith, a waste product from coconut fiber processing. The resulting biocomposite has thermal insulation properties comparable to commercial insulators like Styrofoam and polyurethane, but is completely biodegradable and made from agricultural waste. This innovation addresses waste management problems while creating a sustainable material for thermal insulation in buildings, food processing, and industrial equipment.

Screening of active components of Ganoderma lucidum and decipher its molecular mechanism to improve learning and memory disorders

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Researchers used computer analysis and laboratory experiments to understand how a medicinal mushroom called Ganoderma lucidum (reishi) helps improve memory and learning problems. They identified ten key active ingredients in the mushroom that work together to reduce inflammation in the brain and protect nerve cells. The most important ingredient appears to be a compound called β-sitosterol, which helps prevent memory loss similar to effects seen in Alzheimer’s disease.

Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

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This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

MycelioTronics: Fungal mycelium skin for sustainable electronics

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Researchers have developed a new type of electronic device substrate made from fungal mycelium, the thread-like root structure of mushrooms. This material is completely biodegradable and can be processed like traditional electronic materials to create flexible circuits and batteries. The mycelium-based devices can power wireless sensors and transmit data via Bluetooth, demonstrating that sustainable electronics can perform just as well as conventional ones while being composted at the end of their life.

Research Progress on the Mechanisms of Polysaccharides against Gastric Cancer

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This review explores how natural polysaccharides from mushrooms, seaweed, plants, and traditional herbs can fight gastric cancer. These compounds work by triggering cancer cell death, stopping tumor growth, and boosting the body’s immune system. Unlike conventional chemotherapy drugs that cause serious side effects, these natural polysaccharides offer a safer alternative that can work alongside existing treatments to improve patient survival.

Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

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Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

Ergothioneine: An Antioxidative, Neuroprotective and Anti-Inflammatory Compound from Mushroom Residuals

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Ergothioneine is a powerful antioxidant found mainly in mushrooms that protects brain health and reduces inflammation. Mushroom processing creates large amounts of waste like stems and leftover substrate that actually contain high levels of this beneficial compound. Scientists have developed sustainable methods to extract ergothioneine from this waste, creating opportunities for new health supplements and functional foods while reducing waste and supporting environmental sustainability.

Fungal Species: Ganoderma lucidum