Fungal Species:  Ganoderma applanatum

Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

Mushrooms and related fungi in the basidiomycete group produce many useful medicines and agricultural chemicals. Scientists have traditionally struggled to study these fungi because they grow slowly and have complex genomes. Recent technological breakthroughs—including faster DNA sequencing and gene-editing tools—are now making it much easier to discover and understand the helpful compounds these fungi produce, potentially leading to new medicines.

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Comparative Mitogenomics Provides Valuable Insights for the Phylogeny and New DNA Barcodes of Ganoderma

Researchers successfully sequenced the mitochondrial genomes of four commonly cultivated medicinal mushroom species in the Ganoderma genus. They identified two specific genes, atp9 and nad4L, as reliable molecular barcodes that can accurately distinguish between different Ganoderma species. These DNA barcodes serve as a universal identification tool, similar to product barcodes in supermarkets, helping to identify and classify Ganoderma species for medicinal and commercial purposes.

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Ganoderma lucidum Mycelia Mass and Bioactive Compounds Production through Grape Pomace and Cheese Whey Valorization

Researchers successfully grew Ganoderma lucidum mushrooms using leftover materials from wine and cheese production instead of expensive lab chemicals. The mushroom mycelium produced valuable compounds called polysaccharides that have antioxidant and health-promoting properties. This approach reduces food waste while creating beneficial substances, making it economically and environmentally sustainable.

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First Report of Ganoderma ryvardenii causing Basal Stem Rot (BSR) disease on oil palm (Elaeis guineensis Jacq.) in Ghana

Oil palm is a valuable crop, but a fungal disease called basal stem rot (BSR) causes serious damage and economic losses. Researchers in Ghana discovered that a fungus species called Ganoderma ryvardenii is causing BSR disease on oil palms, marking the first time this pathogen has been found in West Africa. The study used modern genetic testing to identify the fungus and proved it causes the disease by infecting oil palm seedlings in controlled conditions.

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Amylase-assisted extraction alters nutritional and physicochemical properties of polysaccharides and saponins isolated from Ganoderma spp

Researchers studied how enzyme treatment improves extraction of beneficial compounds from reishi mushrooms. They found that using amylase enzyme significantly increased the amounts of healthy polysaccharides and saponins recovered, especially from cultivated black reishi canopies. These extracted compounds work as natural emulsifiers comparable to lecithin and remain stable even at very high temperatures, making them promising ingredients for functional foods and health products.

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Biotechnological Applications of Mushrooms under the Water-Energy-Food Nexus: Crucial Aspects and Prospects from Farm to Pharmacy

Mushrooms are emerging as a powerful solution for solving global food, water, and energy challenges. Scientists are using biotechnology to produce tiny healing particles from mushrooms, clean up polluted soil and water, create renewable energy, and extract beneficial compounds for medicine and health. This review shows how integrated mushroom farming can help achieve sustainable development goals while reducing waste and supporting human wellbeing.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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Biologically active secondary metabolites from white-rot fungi

White-rot fungi are special mushrooms that can break down wood and produce unique chemical compounds with amazing health benefits. These compounds have been found to fight cancer, kill harmful bacteria, reduce inflammation, and protect nerve cells. Scientists are excited about using these natural fungal compounds to create new medicines and treat various diseases in the future.

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Bioactivity and toxicity of polysaccharides derived from the phytopathogenic mushroom Ganoderma orbiforme cultured in a bioreactor

Scientists studied a mushroom called Ganoderma orbiforme that normally harms oil palm trees to see if it could be useful as medicine. They grew the mushroom in a special bioreactor and extracted beneficial substances called polysaccharides. These substances showed promise as natural antibiotics and antioxidants while being safe for use based on safety testing with fish embryos.

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Solid-state fermentation of hemp waste: enhancing the performance of Hermetia illucens larvae and altering the composition of hemp secondary metabolites

Researchers tested whether fermenting hemp plant waste with different mushroom types could make it a better food source for black soldier fly larvae, which produce valuable protein for animal feed. They found that different mushroom species had different effects: Ganoderma lucidum significantly increased the amount of larvae produced, while Trichoderma reesei increased beneficial cannabinoid content. Pleurotus ostreatus and Hypsizygus ulmarius removed unwanted cannabinoids from the waste. This approach offers a promising way to turn hemp waste into high-quality insect feed while controlling the levels of bioactive compounds.

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