Ganoderma applanatum

Edible Mushrooms as a Potential Component of Dietary Interventions for Major Depressive Disorder

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This review examines how edible mushrooms, particularly Lion’s mane, Reishi, and Caterpillar mushroom, might help treat depression as part of a dietary approach. These mushrooms contain compounds that may influence brain chemistry, especially serotonin levels, which are important for mood regulation. While early studies show promising results, especially for Lion’s mane, more research is needed to confirm these benefits in larger groups of patients.

Ganoapplanilactone C from Ganoderma applanatum Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease via AMPK/mTOR-Mediated Lipid Regulation in Zebrafish

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Researchers found that a compound called ganoapplanilactone C from the medicinal mushroom Ganoderma applanatum can protect the liver from fat accumulation and damage caused by high-fat diets. In zebrafish studies, this compound worked better than a common cholesterol drug at reducing liver fat and improving liver health. The compound appears to work by activating a protein called AMPK that helps regulate how the body processes fats and reduces inflammation.

Transcriptome and Metabolome Reveal Accumulation of Key Metabolites with Medicinal Properties of Phylloporia pulla

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Scientists studied a medicinal fungus called Phylloporia pulla to understand which health-promoting compounds it produces and how it makes them. Using advanced genetic and chemical analysis tools, they discovered the fungus produces beneficial compounds like steroids and triterpenoids that have anti-inflammatory and anti-cancer properties, with production peaking around the middle of the fungus’s growth cycle. They identified six key genes that control the production of celastrol, a particularly valuable compound with potential to treat diseases like Alzheimer’s and cancer. This research helps explain why this fungus has been used traditionally in medicine and provides guidance for growing it to maximize production of these beneficial compounds.

Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

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This study tested 30 different mushroom species to determine which ones are the best sources of natural antioxidants that can help protect the body from damage caused by harmful free radicals. Researchers grew the mushrooms in laboratory conditions and measured their antioxidant power and beneficial compounds like polyphenols and polysaccharides. Oyster-like mushrooms called Lentinula edodes and Fomitopsis pinicola showed the strongest antioxidant activity, making them promising candidates for use in health supplements and functional foods.

Benzothiazole—An Antifungal Compound Derived from Medicinal Mushroom Ganoderma lucidum against Mango Anthracnose Pathogen Colletotrichum gloeosporioides

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Scientists discovered that a chemical called benzothiazole found in the medicinal mushroom Ganoderma lucidum can effectively kill the fungus that causes mango anthracnose, a major disease affecting mango crops. The research showed that this natural compound completely stops fungal growth at very low concentrations (50 ppm) and prevents spore germination. This discovery offers a promising eco-friendly alternative to synthetic fungicides that can cause environmental pollution and drug resistance.

Use of Medicinal Mushrooms in Layer Ration

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This review discusses how medicinal mushrooms can be added to chicken feed to improve egg production and boost chicken health, offering a natural alternative to antibiotics. Several types of mushrooms like shiitake and oyster mushrooms have been shown to increase egg quality, strengthen immunity against diseases, and reduce cholesterol in eggs. These findings support the use of mushrooms as a sustainable solution for organic egg farming without compromising production or health.

Edible mushrooms as emerging biofactories for natural therapeutics and oral biopharmaceutical delivery

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Mushrooms are emerging as natural medicine factories that can be genetically engineered to produce medications taken by mouth. Beyond their traditional use as health foods, scientists are now using advanced genetic techniques to program mushrooms to manufacture therapeutic proteins and vaccines. These engineered mushrooms can naturally package and protect these medications as they pass through the stomach, releasing them safely in the intestines for absorption. This approach offers a sustainable, affordable, and cold-chain-independent alternative to conventional injected medications.

Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

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Researchers used mushroom extracts to create tiny zinc oxide particles in an environmentally friendly way. These nanoparticles were tested in mice with liver damage and showed significant protective effects. The particles also demonstrated strong abilities to fight bacteria and fungal infections while acting as powerful antioxidants, suggesting potential use in future medical treatments.

Unlocking the biodegradative potential of native white-rot fungi: a comparative study of fiberbank organic pollutant mycoremediation

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Swedish researchers tested 26 types of white-rot fungi to clean up polluted sediments from old pulp and paper mills called fiberbanks. These contaminated sediments contain harmful chemicals and heavy metals. The study found that three fungal species, especially Diplomitoporus crustulinus, were excellent at breaking down pollutants and could tolerate the toxic environment, making them promising for environmental cleanup efforts.

Evaluation of Bioactive Compounds, Antioxidant Activity, and Anticancer Potential of Wild Ganoderma lucidum Extracts from High-Altitude Regions of Nepal

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Researchers studied a medicinal mushroom called Ganoderma lucidum (Reishi) collected from high mountains in Nepal to understand its health benefits. They tested different ways to extract beneficial compounds from the mushroom and found that using ethanol was most effective. The extracts showed strong cancer-fighting properties against cervical cancer cells and powerful antioxidant effects that may help protect the body from damage. These findings suggest this Himalayan mushroom has real therapeutic potential for treating cancer and other diseases.

Fungal Species: Ganoderma applanatum